Evidence map›Paper›PMID 33114857›Full record

ArticleOptics express2020

Simultaneous stimulated Raman gain and loss detection (SRGAL).

Sandro Heuke, Alberto Lombardini, Edlef Büttner, Hervé Rigneault

Abstract read
In one paragraph

Article in Optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sandro Heuke
Alberto Lombardini
Edlef Büttner
Hervé Rigneault

Funding

Deep-tissue super-resolved microscopy with multiphoton spatial frequency-modulated imaging (MP-SPIFI)R21MH117786 · NIMH · COLORADO STATE UNIVERSITY · PI BARTELS, RANDY A. · 2018 to 2019
$362k
Unrestricted super-resolution imaging deep in tissues through scattering immune spatial frequency modulated imagingR21EB025389 · NIBIB · COLORADO STATE UNIVERSITY · PI BARTELS, RANDY A. · 2018 to 2019
$362k
NIBIB NIH HHS R21 EB025389NIMH NIH HHS R21 MH117786
6 · The paper itself

Abstract

The fidelity of stimulated Raman scattering (SRS) microscopy images is impaired by artifacts such as thermal lensing, cross-phase modulation and multi-photon absorption. These artifacts affect differently the stimulated Raman loss (SRL) and stimulated Raman gain (SRG) channels making SRL and SRG image comparisons attractive to identify and correct SRS image artifacts. To provide answer to the question: "Can I trust my SRS images?", we designed a novel, but straightforward SRS scheme that enables the dectection of the stimulated Raman gain and loss (SRGAL) simultaneously at the same pixel level. As an advantage over the conventional SRS imaging scheme, SRGAL doubles the SRS signal by acquiring both SRL as well as SRG and allows for the identification of SRS artifacts and their reduction via a balanced summation of the SRL and SRG images.

Identifiers

PMID33114857
PMCPMC7679185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.