Evidence map›Paper›PMID 33114775›Full record

ArticleCancers2020

Prognostic Stratification of Bladder Cancer Patients with a MicroRNA-based Approach.

Ilaria Cavallari, Angela Grassi, Paola Del Bianco, Alberto Aceti, Carlotta Zaborra, Evgeniya Sharova, Irene Bertazzolo, Donna M D'Agostino, Massimo Iafrate, Vincenzo Ciminale

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Review
  5. Comparative efficacy of radical prostatectomy and radiotherapy in the treatment of high-risk prostate cancer.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ilaria CavallariVeneto Institute of Oncology IOV-IRCCS, 35128, Padua, Italy.
Angela GrassiVeneto Institute of Oncology IOV-IRCCS, 35128, Padua, Italy.
Paola Del BiancoVeneto Institute of Oncology IOV-IRCCS, 35128, Padua, Italy.
Alberto AcetiDepartment of Surgery, Oncology and Gastroenterology, University of Padua, 35128 Padua, Italy.
Carlotta ZaborraDepartment of Surgery, Oncology and Gastroenterology, University of Padua, 35128 Padua, Italy.ORCID 0000-0002-4645-1945
Evgeniya SharovaVeneto Institute of Oncology IOV-IRCCS, 35128, Padua, Italy.
Irene BertazzoloVeneto Institute of Oncology IOV-IRCCS, 35128, Padua, Italy.
Donna M D'AgostinoDepartment of Biomedical Sciences, University of Padua, 35131 Padua, Italy.
Massimo IafrateDepartment of Surgery, Oncology and Gastroenterology, University of Padua, 35128 Padua, Italy.
Vincenzo CiminaleVeneto Institute of Oncology IOV-IRCCS, 35128, Padua, Italy.
Istituto Oncologico Veneto · ITUniversity of Padua · IT

Funding

Istituto Oncologico Veneto 5x1000University of Padova SID16_01 and BIRD 205490
6 · The paper itself

Abstract

Robust non-invasive tests for prognostic stratification of bladder cancer (BCa) patients are in high demand. Following a comprehensive analysis of studies on BCa, we selected a panel of 29 microRNAs (miRNAs) and analyzed their levels in urine and plasma samples in a prospective cohort of 63 BCa patients (32 at high risk of recurrence and 31 low-risk cases) and 37 healthy controls using RT-qPCR. To design an assay suitable for large-scale testing, we applied a hierarchical pipeline to select the miRNAs that were not affected by confounding factors such as haematuria and urine specific gravity, and exceeded stringent cut-off criteria (fold change >2.5 and

Indexed as

bladder cancerliquid biopsymicroRNAsprognostic stratification

Identifiers

PMID33114775
PMCPMC7692037
OpenAlexW3096930927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.