Evidence map›Paper›PMID 33114668›Full record

ArticleMolecules (Basel, Switzerland)2020

Design and Synthesis of Various 5'-Deoxy-5'-(4-Substituted-1,2,3-Triazol-1-yl)-Uridine Analogues as Inhibitors of

Vincent Hervin, Ritu Arora, Jyoti Rani, Srinivasan Ramchandran, Urmi Bajpai, Luigi A Agrofoglio, Vincent Roy

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Vincent HervinInstitute of Organic and Analytical Chemistry, CNRS UMR 7311, Universite d'Orléans, Rue de Chartres, CEDEX 2, 45067 Orleans, France.
Ritu AroraDepartment of Biomedical Science, Acharya Narendra Dev College, University of Delhi, New Delhi 110019, India.
Jyoti RaniDepartment of Biomedical Science, Acharya Narendra Dev College, University of Delhi, New Delhi 110019, India.
Srinivasan RamchandranG N Ramachandran Knowledge of Centre, Council of Scientific and Industrial Research-Institute of Genomics and Integrative Biology (CSIR-IGIB), Room No. 130, Mathura Road, New Delhi 110025, India.
Urmi BajpaiDepartment of Biomedical Science, Acharya Narendra Dev College, University of Delhi, New Delhi 110019, India.
Luigi A AgrofoglioInstitute of Organic and Analytical Chemistry, CNRS UMR 7311, Universite d'Orléans, Rue de Chartres, CEDEX 2, 45067 Orleans, France.ORCID 0000-0002-6083-0810
Vincent RoyInstitute of Organic and Analytical Chemistry, CNRS UMR 7311, Universite d'Orléans, Rue de Chartres, CEDEX 2, 45067 Orleans, France.ORCID 0000-0002-2491-6019
Université d'Orléans · FRUniversity of Delhi · INInstitute of Genomics and Integrative Biology · IN

Funding

Agence Nationale de la Recherche ANR-11-LABX-0029
6 · The paper itself

Abstract

The synthesis of hitherto unknown 5'-deoxy-5'-(4-substituted-1,2,3-triazol-1-yl)-uridine and its evaluation, through an one-pot screening assay, against MurA-F enzymes involved in

Indexed as

Drug DesignCatalytic DomainChemistry Techniques, SyntheticEnzyme InhibitorsMolecular Docking SimulationMycobacterium tuberculosisPeptide SynthasesTriazolesUridineEnzyme InhibitorsPeptide SynthasesTriazolesUridineantibacterial agentscopper-catalyzed azide-alkyne cycloadditionmolecular modellingMur ligasenucleoside analogues

Identifiers

PMID33114668
PMCPMC7663697
OpenAlexW3095560602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.