ArticleInternational journal of environmental research and public health2020
Work Ability Assessment and Its Relationship with Cardiovascular Autonomic Profile in Postural Orthostatic Tachycardia Syndrome.
Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 28 citations in OpenAlex.
- Utility and best practices for clinical diagnostic testing of the autonomic nervous system: A Consensus Statement Endorsed by the American Autonomic Society and the American Association of Neuromuscular & Electrodiagnostic Medicine.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Review
- Short and long term effects of a two-week transcutaneous vagus nerve stimulation in hyperadrenergic postural orthostatic tachycardia syndrome: a proof-of-concept trial.European journal of internal medicine · 2026Article
- Long-Term Postural Orthostatic Tachycardia Syndrome Outcomes Survey: Educational, Economic, and Social Impact.Journal of the American Heart Association · 2025Article
- Effects of different postures on the hemodynamics and cardiovascular autonomic control responses to exercise in postural orthostatic tachycardia syndrome.European journal of applied physiology · 2025Article
- Work ability during the COVID-19 pandemic: A cross-sectional study in a low-income urban setting in Brazil.PloS one · 2025Article
- The Diagnostic Journey of Dysautonomia Patients: Insights from a Patient-Reported Outcome Study.Journal of patient experience · 2025Article
- The effects of vitamin B and D supplementations on autonomic functions and quality of life in children after vasovagal syncope.Frontiers in pediatrics · 2025Article
- SARS-CoV-2 Infection and Alpha-Synucleinopathies: Potential Links and Underlying Mechanisms.International journal of molecular sciences · 2024Review
- One Size Does Not Fit All: An Exploration of Compression Garment Use in Patients With Postural Orthostatic Tachycardia Syndrome.CJC open · 2024Article
- Poor Work Ability Is Associated with Workplace Violence in Nurses: A Two-Wave Panel Data Analysis.International journal of environmental research and public health · 2024Article
- Article
- Long-COVID autonomic syndrome in working age and work ability impairment.Scientific reports · 2024Observational
- Autonomic neuropathy improving after intravenous immunoglobulin therapy.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024Article
- The Work Ability Index (WAI) in the Healthcare Sector: A Cross-Sectional/Retrospective Assessment of the Questionnaire.International journal of environmental research and public health · 2024Article
- Detecting Orthostatic Intolerance in Long COVID in a Clinic Setting.International journal of environmental research and public health · 2023Article
- Transdermal auricular vagus stimulation for the treatment of postural tachycardia syndrome.Autonomic neuroscience : basic & clinical · 2021Article
- Relationships Between Cardiovascular Autonomic Profile and Work Ability in Patients With Pure Autonomic Failure.Frontiers in human neuroscience · 2021Article
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postural orthostatic tachycardia syndrome (POTS) negatively impacts quality of life. The excessive increase in cardiac sympathetic modulation during standing, which characterizes POTS patients, leads to many symptoms and signs of orthostatic intolerance. Little is known about the consequences of the disease on work performance and its relationship with individual autonomic profiles. Twenty-two POTS patients regularly engaged in working activity (20 females, age 36 ± 12 years) and 18 gender- and age-matched controls underwent a clinical evaluation and filled out the Work Ability Index (WAI) questionnaire. POTS patients completed the Composite Autonomic Symptom Score (COMPASS31) questionnaire, underwent continuous electrocardiogram, blood pressure and respiratory activity recordings while supine and during a 75° head-up tilt (HUT). A power spectrum analysis provided the index of cardiac sympatho-vagal balance (LF/HF). WAI scores were significantly reduced in POTS patients (29.84 ± 1.40) compared to controls (45.63 ± 0.53, p < 0.01). A significant inverse correlation was found between individual WAI and COMPASS31 scores (r = -0.46; p = 0.03), HUT increase in heart rate (r = -0.57; p = 0.01) and LF/HF (r = -0.55; p = 0.01). In POTS patients, the WAI scores were inversely correlated to the intensity of autonomic symptoms and to the excessive cardiac sympathetic activation induced by the gravitational stimulus.
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