Evidence map›Paper›PMID 33114581›Full record

ArticleBiomolecules2020

Silkworm Pupae Function as Efficient Producers of Recombinant Glycoproteins with Stable-Isotope Labeling.

Hirokazu Yagi, Saeko Yanaka, Rina Yogo, Akari Ikeda, Masayoshi Onitsuka, Toshio Yamazaki, Tatsuya Kato, Enoch Y Park, Jun Yokoyama, Koichi Kato

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Hirokazu YagiGraduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya 467-8603, Japan.ORCID 0000-0001-9296-0225
Saeko YanakaGraduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya 467-8603, Japan.ORCID 0000-0002-3513-5701
Rina YogoGraduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya 467-8603, Japan.ORCID 0000-0002-1595-0194
Akari IkedaTaiyo Nippon Sanso Corporation, SI Innovation Center, 2008-2 Wada, Tama, Tokyo 206-0001, Japan.
Masayoshi OnitsukaGraduate School of Technology, Industrial and Social Sciences, Tokushima University, Minamijosanjima-cho 2-1, Tokushima 770-8513, Japan.ORCID 0000-0003-4220-1401
Toshio YamazakiSPring-8 Center RIKEN, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa 230-0045, Japan.
Tatsuya KatoLaboratory of Biotechnology, Research Institute of Green Science and Technology, Shizuoka University, 836 Ohya Suruga-ku, Shizuoka 422-8529, Japan.ORCID 0000-0001-7990-2557
Enoch Y ParkLaboratory of Biotechnology, Research Institute of Green Science and Technology, Shizuoka University, 836 Ohya Suruga-ku, Shizuoka 422-8529, Japan.ORCID 0000-0002-7840-1424
Jun YokoyamaTaiyo Nippon Sanso Corporation, SI Innovation Center, 2008-2 Wada, Tama, Tokyo 206-0001, Japan.
Koichi KatoGraduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya 467-8603, Japan.ORCID 0000-0001-7187-9612
National Institutes of Natural Sciences · JPShizuoka University · JPNagoya City University · JPNHK Spring (Japan) · JPTokushima University · JP

Funding

Exploratory Research Center on Life and Living Systems (ExCELLS) 20-308Ministry of Education, Culture, Sports, Science and Technology JP18K14892, JP20K15981, JP19H01017, JP19J15602Nanotechnology Platform Program (Molecule and Material Synthesis) of MEXT, Advanced NMR Application and Platform PF17-01-R-008, PF19-01-R-022
6 · The paper itself

Abstract

Baculovirus-infected silkworms are promising bioreactors for producing recombinant glycoproteins, including antibodies. Previously, we developed a method for isotope labeling of glycoproteins for nuclear magnetic resonance (NMR) studies using silkworm larvae reared on an artificial diet containing

Indexed as

Isotope LabelingAnimalsBombyxGlycoproteinsPupaRecombinant ProteinsGlycoproteinsRecombinant Proteinsartificial dietimmunoglobulin Gisotope labelingrecombinant glycoproteinsilkworm pupa

Identifiers

PMID33114581
PMCPMC7692867
OpenAlexW3097421893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.