ArticlePathogens (Basel, Switzerland)2020
Covid-19: Fat, Obesity, Inflammation, Ethnicity, and Sex Differences.
Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 27 citations in OpenAlex.
- Association of excess visceral fat and severe illness in hospitalized COVID-19 patients in Japan: a retrospective cohort study.International journal of obesity (2005) · 2024Article
- The effect of yin yoga intervention on state and trait anxiety during the COVID-19 pandemic.Frontiers in psychiatry · 2024Article
- New insights into the pathogenesis of SARS-CoV-2 during and after the COVID-19 pandemic.Frontiers in immunology · 2024Review
- Visceral fat area measured by electrical bioimpedance as an aggravating factor of COVID-19: a study on body composition.BMC infectious diseases · 2023Article
- Determinants of survival in patients on extracorporeal membrane oxygenation therapy due to severe covid-19.Perfusion · 2023Article
- What is the role of brown adipose tissue in metabolic health: lessons learned and future perspectives in the long COVID?Inflammopharmacology · 2023Review
- What is the role of brown adipose tissue in metabolic health: lessons learned and future perspectives in the long COVID?Inflammopharmacology · 2023Review
- COVID-19, Anosmia, and Allergies: Is There a Relationship? A Pediatric Perspective.Journal of clinical medicine · 2022Article
- Article
- Investigation on the Factors Associated with the Persistence of Anosmia and Ageusia in Saudi COVID-19 Patients.International journal of environmental research and public health · 2022Article
- How culturally unique are pandemic effects? Evaluating cultural similarities and differences in effects of age, biological sex, and political beliefs on COVID impacts.Frontiers in psychology · 2022Article
- Dysautonomia and Implications for Anosmia in Long COVID-19 Disease.Journal of clinical medicine · 2021Review
- An Overview of Adipose Tissue ACE2 Modulation by Diet and Obesity. Potential Implications in COVID-19 Infection and Severity.International journal of molecular sciences · 2021Review
- Cross-National Variations in COVID-19 Mortality: The Role of Diet, Obesity and Depression.Diseases (Basel, Switzerland) · 2021Article
- The Inflammatory Profile of Obesity and the Role on Pulmonary Bacterial and Viral Infections.International journal of molecular sciences · 2021Review
- The Obesity Paradox Predicts the Second Wave of COVID-19 to Be Severe in Western Countries.International journal of environmental research and public health · 2021Article
- Ethnicity-Specific Features of COVID-19 Among Arabs, Africans, South Asians, East Asians, and Caucasians in the United Arab Emirates.Frontiers in cellular and infection microbiology · 2021Article
- Pandemic Leadership: Sex Differences and Their Evolutionary-Developmental Origins.Frontiers in psychology · 2021Review
- Do Islanders Have a More Reactive Behavioral Immune System? Social Cognitions and Preferred Interpersonal Distances During the COVID-19 Pandemic.Frontiers in psychology · 2021Article
- COVID-19 Pandemic on Fire: Evolved Propensities for Nocturnal Activities as a Liability Against Epidemiological Control.Frontiers in psychology · 2021Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
Abstract
Although obesity is known to be a risk factor for COVID-19 severity, there is an urgent need to distinguish between different kinds of fat-visceral and subcutaneous fat-and their inflammation status in COVID-19. These different fat types have partially diverging biochemical roles in the human body, and they are differentially associated with SARS-CoV-2, which targets the angiotensin-converting enzyme 2 (ACE2) for cell entry. ACE2 is highly expressed in adipose tissue, especially in visceral fat, suggesting an important role for this tissue in determining COVID-19 disease severity. In this perspective article, we discuss group differences in the amount of visceral fat levels and the extent of inflammation in adipocytes of visceral fat tissue, which may, in part, drive population, cross-national, ethnic, and sex differences in COVID-19 disease. It is vital to steer the scientific community's attention to the effects of visceral fat in creating individual and population differences in COVID-19 severity. This can help researchers unravel the reasons for the reported population, ethnic, and sex differences in COVID-19 severity and mortality.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.