Evidence map›Paper›PMID 33114407›Full record

ReviewPharmaceutics2020

Preclinical and Clinical Applications of Biomaterials in the Enhancement of Wound Healing in Oral Surgery: An Overview of the Available Reviews.

Giacomo Picciolo, Matteo Peditto, Natasha Irrera, Giovanni Pallio, Domenica Altavilla, Mario Vaccaro, Giuseppe Picciolo, Alessandro Scarfone, Francesco Squadrito, Giacomo Oteri

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giacomo PiccioloDepartment of Biomedical and Dental Sciences and Morphological and Functional Imaging, University of Messina, Via C. Valeria, 98125 Messina, Italy.
Matteo PedittoDepartment of Biomedical and Dental Sciences and Morphological and Functional Imaging, University of Messina, Via C. Valeria, 98125 Messina, Italy.
Natasha IrreraDepartment of Clinical and Experimental Medicine, University of Messina, Via C. Valeria, 98125 Messina, Italy.
Giovanni PallioDepartment of Clinical and Experimental Medicine, University of Messina, Via C. Valeria, 98125 Messina, Italy.ORCID 0000-0002-4187-2265
Domenica AltavillaDepartment of Biomedical and Dental Sciences and Morphological and Functional Imaging, University of Messina, Via C. Valeria, 98125 Messina, Italy.
Mario VaccaroDepartment of Clinical and Experimental Medicine, University of Messina, Via C. Valeria, 98125 Messina, Italy.
Giuseppe PiccioloSunNutraPharma, Academic Spin-Off Company of the University of Messina, Via C. Valeria, 98125 Messina, Italy.
Alessandro ScarfoneDepartment of Clinical and Experimental Medicine, University of Messina, Via C. Valeria, 98125 Messina, Italy.
Francesco SquadritoDepartment of Clinical and Experimental Medicine, University of Messina, Via C. Valeria, 98125 Messina, Italy.ORCID 0000-0002-8868-0762
Giacomo OteriDepartment of Biomedical and Dental Sciences and Morphological and Functional Imaging, University of Messina, Via C. Valeria, 98125 Messina, Italy.ORCID 0000-0002-0941-1645

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral surgery has undergone dramatic developments in recent years due to the use of biomaterials. The aim of the present review is to provide a general overview of the current biomaterials used in oral surgery and to comprehensively outline their impact on post-operative wound healing. A search in Medline was performed, including hand searching. Combinations of searching terms and several criteria were applied for study identification, selection, and inclusion. The literature was searched for reviews published up to July 2020. Reviews evaluating the clinical and histological effects of biomaterials on post-operative wound healing in oral surgical procedures were included. Review selection was performed by two independent reviewers. Disagreements were resolved by a third reviewer, and 41 reviews were included in the final selection. The selected papers covered a wide range of biomaterials such as stem cells, bone grafts, and growth factors. Bioengineering and biomaterials development represent one of the most promising perspectives for the future of oral surgery. In particular, stem cells and growth factors are polarizing the focus of this ever-evolving field, continuously improving standard surgical techniques, and granting access to new approaches.

Indexed as

biomaterialsoral surgeryoral wound healing

Identifiers

PMID33114407
PMCPMC7692581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.