Evidence map›Paper›PMID 33114403›Full record

ArticleBiomedicines2020

Modulation of Small RNA Signatures in Schwann-Cell-Derived Extracellular Vesicles by the p75 Neurotrophin Receptor and Sortilin.

Nádia P Gonçalves, Yan Yan, Maj Ulrichsen, Morten T Venø, Ebbe T Poulsen, Jan J Enghild, Jørgen Kjems, Christian B Vægter

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. NGF and Its Role in Immunoendocrine Communication during Metabolic Syndrome.International journal of molecular sciences · 2023
    Review
  7. Article
  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nádia P GonçalvesDanish Research Institute of Translational Neuroscience (DANDRITE), Nordic-EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.ORCID 0000-0002-5534-958X
Yan YanInterdisciplinary Nanoscience Centre (iNANO), Aarhus University, 8000 Aarhus, Denmark.
Maj UlrichsenDanish Research Institute of Translational Neuroscience (DANDRITE), Nordic-EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.
Morten T VenøInterdisciplinary Nanoscience Centre (iNANO), Aarhus University, 8000 Aarhus, Denmark.
Ebbe T PoulsenDepartment of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus, Denmark.ORCID 0000-0002-4416-0431
Jan J EnghildDepartment of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus, Denmark.
Jørgen KjemsInterdisciplinary Nanoscience Centre (iNANO), Aarhus University, 8000 Aarhus, Denmark.ORCID 0000-0003-4128-9317
Christian B VægterDanish Research Institute of Translational Neuroscience (DANDRITE), Nordic-EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.ORCID 0000-0001-6573-146X
Aarhus University · DK

Funding

Aarhus Universitets Forskningsfond AUFF-E-2015-FLS-8-4Dagmar Marshalls Fond -Danmarks Frie Forskningsfond 8020-00118BFoundation for Research in Neurology -Innovationsfonden MUSTER-Musculoskeletal stem cell targeting
6 · The paper itself

Abstract

Schwann cells (SCs) are the main glial cells of the peripheral nervous system (PNS) and are known to be involved in various pathophysiological processes, such as diabetic neuropathy and nerve regeneration, through neurotrophin signaling. Such glial trophic support to axons, as well as neuronal survival/death signaling, has previously been linked to the p75 neurotrophin receptor (p75

Indexed as

exosomesextracellular vesicles (EVs)miRNAsp75NTR receptorSchwann cellssortilin

Identifiers

PMID33114403
PMCPMC7694014
OpenAlexW3093685058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.