Evidence map›Paper›PMID 33114391›Full record

ArticlePathogens (Basel, Switzerland)2020

Effectiveness of Chemical Compounds Used against African Swine Fever Virus in Commercial Available Disinfectants.

Małgorzata Juszkiewicz, Marek Walczak, Natalia Mazur-Panasiuk, Grzegorz Woźniakowski

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
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  10. Article
  11. Article
  12. Antiviral activity of SAFERFrontiers in veterinary science · 2024
    Article
  13. Review
  14. Article
  15. Review
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  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Małgorzata JuszkiewiczDepartment of Swine Diseases, National Veterinary Research Institute, Partyzantów 57 Avenue, 24-100 Puławy, Poland.ORCID 0000-0002-5705-4099
Marek WalczakDepartment of Swine Diseases, National Veterinary Research Institute, Partyzantów 57 Avenue, 24-100 Puławy, Poland.ORCID 0000-0002-2991-9964
Natalia Mazur-PanasiukDepartment of Swine Diseases, National Veterinary Research Institute, Partyzantów 57 Avenue, 24-100 Puławy, Poland.
Grzegorz WoźniakowskiDepartment of Swine Diseases, National Veterinary Research Institute, Partyzantów 57 Avenue, 24-100 Puławy, Poland.ORCID 0000-0002-1333-4275

Funding

Państwowy Instytut Weterynaryjny - Państwowy Instytut Badawczy The study was supported by the subsidy on maintenance of the research potential S/385: "Development and improvement of the methodology for testing the virucidal activity of disinfectants against the African swine fever virus (ASFV)"
6 · The paper itself

Abstract

African swine fever (ASF) causes huge economic losses and is one of most dangerous diseases of pigs. The disease is known for almost 100 years, an effective vaccine or treatment is still unavailable, only proper biosecurity measures, including disinfection, are being applied, in order to prevent disease outbreaks. Eight active substances, i.e., formaldehyde, sodium hypochlorite, caustic soda, glutaraldehyde, phenol, benzalkonium chloride, potassium peroxymonosulfate and acetic acid, were tested, in order to confirm their effectiveness against African swine fever virus (ASFV). This specific selection was done based on the World Organisation for Animal Health (OIE)'s recommendation and previous disinfectant studies on surfaces. The result of our study shows that most of them inactivate the virus, in recommended concentrations. In order to reduce the cytotoxicity of the four substances, Microspin S-400 HR columns were applied, therefore making it possible to demonstrate four logarithms virus titer reduction. Sodium hypochlorite, glutaraldehyde, caustic soda and potassium peroxymonosulfate showed the best ASFV inactivation rates, achieving titer reductions over 5 logs. Despite microfiltration, the virucidal activity of formaldehyde was not assessable, due to its high cytotoxicity. Our results showed that cleaning is particularly important, because removal of the soiling provides improved effectiveness of the tested chemical compounds.

Indexed as

African swine feverASFbiosecuritydisinfectionin vitro infectivitysuspension testvirucidal effects

Identifiers

PMID33114391
PMCPMC7693804

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.