ArticleMedicina (Kaunas, Lithuania)2020
Major Clues and Pitfalls in the Differential Diagnosis of Parathyroid and Thyroid Lesions Using Fine Needle Aspiration Cytology.
Article in Medicina (Kaunas, Lithuania), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- Large atypical parathyroid tumor mimicking metastatic papillary thyroid carcinoma: a case report.Journal of medical case reports · 2025Article
- Parathyroid Adenoma with Macrofollicular Growth Pattern: A Rare Histopathological Entity.Journal of the ASEAN Federation of Endocrine Societies · 2025Article
- Radiation-Induced Synchronous Parathyroid Carcinoma and Papillary Thyroid Carcinoma: Clinical, Morphological, and Genetic Insights.International journal of molecular sciences · 2025Article
- Large atypical parathyroid tumor - a diagnostic conundrum.Autopsy & case reports · 2024Article
- Case report: Relapse of intrathyroidal parathyroid carcinoma in a patient with novel variants inFrontiers in oncology · 2024Article
- Remission of primary hyperparathyroidism after fine needle aspiration of a parathyroid nodule mistaken for a thyroid nodule.Archives of endocrinology and metabolism · 2023Article
- Silent intrathyroid parathyroid carcinoma.Endocrinology, diabetes & metabolism case reports · 2023Article
- Immunohistochemical Profile of Parathyroid Tumours: A Comprehensive Review.International journal of molecular sciences · 2022Review
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIt is difficult to distinguish parathyroid lesions (PLs) from thyroid lesions using fine needle aspiration cytology (FNAC) because of their proximity and their similar cytomorphological features.
methodsFNAC smears of 46 patients with pathologically proven PLs that were histologically diagnosed as parathyroid adenoma (PA,
resultsOur initial cytological diagnoses indicated correct diagnoses in 31 of 46 PL patients (67%). The 15 erroneous diagnoses were 5 patients with non-specific benign disease (11%), 4 with nodular hyperplasia of the thyroid (9%), 5 with atypical cells (11%), and 1 with a metastatic papillary thyroid carcinoma (2%). Follicular pattern, papillary structures, colloid-like material, and macrophages, which often suggest thyroid lesions, were also present in some PLs. We found that branching capillaries along the papillary structures, stippled nuclear chromatin, and frequent occurrence of naked nuclei were useful for determining a parathyroid origin.
conclusionsIt is important to be aware that PLs are frequently mistaken for thyroid lesions based on FNAC. The specific and unique characteristics of PLs identified here may be helpful in diagnosis.
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