Evidence map›Paper›PMID 33114336›Full record

ReviewViruses2020

Influenza Vaccines toward Universality through Nanoplatforms and Given by Microneedle Patches.

Sijia Tang, Wandi Zhu, Bao-Zhong Wang

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sijia TangCenter for Inflammation, Immunity & Infection, Georgia State University, Atlanta, GA 30303, USA.
Wandi ZhuCenter for Inflammation, Immunity & Infection, Georgia State University, Atlanta, GA 30303, USA.
Bao-Zhong WangCenter for Inflammation, Immunity & Infection, Georgia State University, Atlanta, GA 30303, USA.ORCID 0000-0002-1561-4318
Georgia State University · US

Funding

Novel Influenza nano vaccines for broad cross protectionR01AI101047 · NIAID · GEORGIA STATE UNIVERSITY · PI WANG, BAOZHONG · 2012 to 2023
$6.1M
Multivalent nanocluster universal influenza vaccine given by microneedle patchR01AI143844 · NIAID · GEORGIA STATE UNIVERSITY · PI WANG, BAOZHONG · 2019 to 2023
$3.9M
Novel vaccine to enhance breadth of influenza immunity by skin vaccinationR01AI116835 · NIAID · GEORGIA STATE UNIVERSITY · PI WANG, BAOZHONG · 2015 to 2018
$2.4M
NIAID NIH HHS R01 AI101047NIAID NIH HHS R01 AI116835NIAID NIH HHS R01 AI143844
6 · The paper itself

Abstract

Influenza is one of the top threats to public health. The best strategy to prevent influenza is vaccination. Because of the antigenic changes in the major surface antigens of influenza viruses, current seasonal influenza vaccines need to be updated every year to match the circulating strains and are suboptimal for protection. Furthermore, seasonal vaccines do not protect against potential influenza pandemics. A universal influenza vaccine will eliminate the threat of both influenza epidemics and pandemics. Due to the massive challenge in realizing influenza vaccine universality, a single vaccine strategy cannot meet the need. A comprehensive approach that integrates advances in immunogen designs, vaccine and adjuvant nanoplatforms, and vaccine delivery and controlled release has the potential to achieve an effective universal influenza vaccine. This review will summarize the advances in the research and development of an affordable universal influenza vaccine.

Indexed as

AnimalsAntibodies, ViralCross ProtectionDrug Delivery SystemsHumansInfluenza, HumanInfluenza VaccinesMiceMicroinjectionsNanotechnologyNeedlesPandemicsVaccinationAntibodies, ViralInfluenza Vaccinesinfluenzamicroneedle patchprotein nanoparticlesuniversal influenza vaccine

Identifiers

PMID33114336
PMCPMC7690886
OpenAlexW3094080625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.