ReviewPlants (Basel, Switzerland)2020
Innovative Extraction Techniques Using Deep Eutectic Solvents and Analytical Methods for the Isolation and Characterization of Natural Bioactive Compounds from Plant Material.
Review in Plants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed.
- Disruption or partitioning? Deep eutectic solvent biphasic systems for integrated seaweed biorefineries.Bioresources and bioprocessing · 2026Article
- Bergapten as a Multifunctional Phytochemical in Cancer Therapy: Mechanistic Insights, Pharmacokinetics, and Possible Nanotechnology-Enabled Formulation Strategies.Pharmaceutics · 2026Review
- Dehydration-driven organization of metabolites into NaDES-like assemblies in orthodox seeds.The New phytologist · 2026Article
- Integrated sonication-assisted deep eutectic solvent for extraction of antibacterial compounds from cacao shells.RSC advances · 2026Article
- Choline Chloride-Based Deep Eutectic Solvents for Efficient Polyphenol Extraction from White Mulberry (Molecules (Basel, Switzerland) · 2026Article
- Deep Eutectic Solvents for Sustainable Extraction of Bioactive Compounds from Biomass: Mechanistic Insights and Scale-Up Challenges.Molecules (Basel, Switzerland) · 2026Review
- From rumen to milk: Dietary polyphenols in dairy cows-A critical review.Veterinary and animal science · 2026Review
- From rosemary and coffee to bioactive nanovesicles: exploring new frontiers in food functional ingredients.NPJ science of food · 2026Article
- Antibacterial, Antioxidant Potential, and Chemodiversity of Aesculus indica Bark Extracts Along the Garhwal Himalayan Altitudinal Gradient.Chemistry & biodiversity · 2026Article
- A deep dive into herbal extraction: Techniques, trends, and technological advancements.South African journal of botany : official journal of the South African Association of Botanists = Suid-Afrikaanse tydskrif vir plantkunde : amptelike tydskrif van die Suid-Afrikaanse Genootskap van Plantkundiges · 2026Article
- Optimization of deep eutectic solvent extraction ofFrontiers in pharmacology · 2026Article
- Green ultrasound‑assisted deep eutectic solvent extraction of flavonoid enzyme inhibitors fromJournal of enzyme inhibition and medicinal chemistry · 2025Article
- Current Status and Future Perspectives of Betaine and Betaine-Based Natural Deep Eutectic Solvents: A Review.Foods (Basel, Switzerland) · 2025Review
- Extraction and Identification of Active Components fromMolecules (Basel, Switzerland) · 2025Article
- Multi-Response Modeling for Bio-Compound Ultrasound-Assisted Extraction (UAE) from Matico (Molecules (Basel, Switzerland) · 2025Article
- Green Extraction and Targeted LC-MS Analysis of Biopesticides in Honey Using Natural Deep Eutectic Solvents.Foods (Basel, Switzerland) · 2025Article
- COSMO-RS Solubility Screening and Coumarin Extraction fromMolecules (Basel, Switzerland) · 2025Article
- Deep Eutectic Solvent Systems as Media for the Selective Extraction of Anti-Inflammatory Bioactive Agents.Molecules (Basel, Switzerland) · 2025Review
- Hydrophilic deep eutectic solvents for bioactive compound extraction from Rubia tinctorum L.Analytical and bioanalytical chemistry · 2025Article
- Combining Carboxylic-Acid-Based Deep Eutectic Solvents and High Temperatures Enhances Phenolic Acid Extraction from Grape Pomace.Antioxidants (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The growing interest of the food, pharmaceutical and cosmetics industries in naturally occurring bioactive compounds or secondary plant metabolites also leads to a growing demand for the development of new and more effective analysis and isolation techniques. The extraction of bioactive compounds from plant material has always been a challenge, accompanied by increasingly strict control requirements for the final products and a growing interest in environmental protection. However, great efforts have been made in this direction and today a considerable number of innovative extraction techniques have been developed using green, environmentally friendly solvents. These solvents include the deep eutectic solvents (DES) and their natural equivalents, the natural deep eutectic solvents (NADES). Due to their adjustable physical-chemical properties and their green character, it is expected that DES/NADES could be the most widely used solvents in the future, not only in extraction processes but also in other research areas such as catalysis, electrochemistry or organic synthesis. Consequently, this review provided an up-to-date systematic overview of the use of DES/NADES in combination with innovative extraction techniques for the isolation of bioactive compounds from various plant materials. The topicality of the field was confirmed by a detailed search on the platform WoS (Web of Science), which resulted in more than 100 original research papers on DES/NADES for bioactive compounds in the last three years. Besides the isolation of bioactive compounds from plants, different analytical methods are presented and discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.