Evidence map›Paper›PMID 33114323›Full record

ArticleJournal of clinical medicine2020

Changes in the Epidemiology of Hepatobiliary Disease Complicating Type 2 Diabetes over 25 Years: The Fremantle Diabetes Study.

Timothy M E Davis, Kirsten E Peters, S A Paul Chubb, Leon A Adams, Gary P Jeffrey, Wendy A Davis

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Timothy M E DavisUniversity of Western Australia Medical School, Fremantle Hospital, Fremantle 6959, WA, Australia.ORCID 0000-0003-0749-7411
Kirsten E PetersUniversity of Western Australia Medical School, Fremantle Hospital, Fremantle 6959, WA, Australia.ORCID 0000-0003-1406-8797
S A Paul ChubbPathWest Laboratory Medicine Western Australia, Fiona Stanley Hospital, Murdoch 6150, WA, Australia.
Leon A AdamsUniversity of Western Australia Medical School, Sir Charles Gairdner Hospital, Nedlands 6009, WA, Australia.
Gary P JeffreyUniversity of Western Australia Medical School, Sir Charles Gairdner Hospital, Nedlands 6009, WA, Australia.
Wendy A DavisUniversity of Western Australia Medical School, Fremantle Hospital, Fremantle 6959, WA, Australia.
The University of Western Australia · AUFiona Stanley Hospital · AU

Funding

National Health and Medical Research Council 513781 and APP1042231
6 · The paper itself

Abstract

objectiveTo determine whether the incidence/outcome of hepatobiliary disease (HBD) has increased over recent decades in community-based Australians with and without type 2 diabetes (T2D).

methodsLongitudinal data from the Fremantle Diabetes Study Phase I (FDS1; recruitment 1993-1996;

resultsHBD IRs for people without diabetes did not change between Phases. The IRR (95% CI) for people with T2D in FDS2 versus FDS1 was 1.30 (1.01-1.68) with the highest IRRs in participants aged <65 years. Non-alcoholic fatty liver disease/steatohepatitis (NAFLD/NASH) events were 54% greater in FDS2 than FDS1 in the presence of greater abdominal adiposity. NAFLD/NASH was coded in one in 11 HBD events in FDS2 and in 10% of HBD deaths (<4% of total mortality).

conclusionsHBD is more frequent in people with versus without T2D and this discrepancy is increasing. Hospitalizations/deaths due to NAFLD/NASH remain uncommon.

Indexed as

hepatobiliary diseaseincidencenon-alcoholic fatty liver diseasetype 2 diabetes

Identifiers

PMID33114323
PMCPMC7690874
OpenAlexW3093911705

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.