Evidence map›Paper›PMID 33114267›Full record

ArticleInternational journal of molecular sciences2020

Circulatory Rejuvenated EPCs Derived from PAOD Patients Treated by CD34

Yin-Chia Chen, Jiunn-Jye Sheu, John Y Chiang, Pei-Lin Shao, Shun-Cheng Wu, Pei-Hsun Sung, Yi-Chen Li, Yi-Ling Chen, Tien-Hung Huang, Kuan-Hung Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Yin-Chia ChenDivision of Thoracic and Cardiovascular Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
Jiunn-Jye SheuDivision of Thoracic and Cardiovascular Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
John Y ChiangDepartment of Computer Science and Engineering, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.ORCID 0000-0002-8719-4017
Pei-Lin ShaoDepartment of Nursing, Asia University, Taichung 41354, Taiwan.
Shun-Cheng WuRegenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.
Pei-Hsun SungInstitute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.ORCID 0000-0002-1989-9752
Yi-Chen LiDepartment of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.ORCID 0000-0002-2335-0172
Yi-Ling ChenInstitute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.
Tien-Hung HuangInstitute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.
Kuan-Hung ChenDepartment of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.ORCID 0000-0002-2527-2825
Hon-Kan YipInstitute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.ORCID 0000-0002-6305-5717
Chang Gung University · TWAsia University · TWNational Sun Yat-sen University · TW

Funding

National Science Council MOST 106-2314-B-182A-108 -MY3
6 · The paper itself

Abstract

This study tested whether circulatory endothelial progenitor cells (EPCs) derived from peripheral arterial occlusive disease (PAOD) patients after receiving combined autologous CD34+ cell and hyperbaric oxygen (HBO) therapy (defined as rejuvenated EPCs) would salvage nude mouse limbs against critical limb ischemia (CLI). Adult-male nude mice (

Indexed as

AnimalsAntigens, CD34Arterial Occlusive DiseasesDisease Models, AnimalEndothelial Progenitor CellsHindlimbHumansHyperbaric OxygenationInjections, IntramuscularIschemiaMaleMiceMice, NudeNeovascularization, PhysiologicPeripheral Arterial DiseaseRegional Blood FlowAntigens, CD34angiogenesiscritical limb ischemiaendothelial progenitor cellshyperbaric oxygen therapynude mice

Identifiers

PMID33114267
PMCPMC7660611
OpenAlexW3093735899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.