ReviewJournal of clinical medicine2020
Efficacy and Patient's Acceptance of Alternative Methods for Caries Removal-a Systematic Review.
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Papain-based Materials Compared With NaOCl-based Materials in Chemo-mechanical Caries Removal: A Randomized Controlled Trial
Clinical Evaluation of Pain Perception and Patient Acceptance During Chemomechanical Caries Removal Using Cariclast Versus Conventional Caries Removal in 2nd Primary Molars With Occlusal Caries in Children: A Randomized Clinical Trial
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Effectiveness of BRIX3000 for chemo-mechanical caries removal: a systematic review and meta-analysis of time and pain outcomes.Clinical oral investigations · 2026Pooled it
- Direct Composite Restorations on Permanent Teeth in the Anterior and Posterior Region - An Evidence-Based Clinical Practice Guideline - Part 2: Recommendations for Composite Processing.The journal of adhesive dentistry · 2024Guideline
- Comparative evaluation of BRIX3000 and Carisolv in chemomechanical caries removal in immature permanent first molars: a randomized controlled trial.BMC oral health · 2025Trial
- Trial
- Analyzing working time and efficient caries removal using a novel bioactive caries detecting dye and air polisher prophy for caries excavation: randomised clinical trial.Clinical oral investigations · 2024Trial
- The effectiveness of Carie-Care™, chemomechanical caries removal technique in primary teeth: randomized controlled clinical trial.BMC oral health · 2023Trial
- Trial
- Article
- Acceptability of oral health care: a scoping review of reviews to inform framework development.BMC oral health · 2026Article
- Optimization of Er: YAG pulse duration and repetition rate for efficient, dentin‑preserving caries removal.Lasers in medical science · 2026Article
- Comparative Efficacy of Er:YAG Laser and Dental Turbine in Pediatric Dentistry: A Systematic Review.Children (Basel, Switzerland) · 2026Review
- Minimally Invasive Chemomechanical Caries Removal in Paediatric Dentistry: A Systematic Review of Papacarie and Brix 3000.Journal of clinical medicine · 2026Review
- Effect of Enzymatic-based chemomechanical caries removal agent on proliferation and osteogenic differentiation of dental pulp stem cells.BMC oral health · 2025Article
- Bond strength to dentin after chemomechanical caries removal.Journal of clinical and experimental dentistry · 2025Article
- Histological Evaluation of Chemo Mechanical Caries Removal with a Babaco-Based Formulation Gel.Gels (Basel, Switzerland) · 2025Article
- Chemomechanical Caries Removal with Enzymatic Technology: A ComparativeInternational journal of clinical pediatric dentistry · 2025Article
- Cost-efficiency analysis of atraumatic restorative treatment with and without chemical-mechanical caries removal agents based on pain and time for selective removal of carious tissue: a public health perspective.Clinical oral investigations · 2025Article
- Effect of enzymatic chemo-mechanical agents on adhesion of composite resin to dentin of permanent teeth: an in vitro study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Article
- High-intensity focused ultrasound: an innovative approach for micro-manipulation of demineralized dentine.Journal of translational medicine · 2025Article
- Accuracy of laser fluorescence in assessment of various caries removal techniques: an in vitro validation.BMC oral health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dental caries is a disease of dental hard tissues, considered the most common non-communicable disease worldwide. Conventional treatments for caries removal are often associated with pain and fear, so different therapeutic approaches have been developed towards more conservative and pleasant treatments. This systematic review aimed to assess the efficacy and patient's acceptance of alternative methods for caries removal compared to conventional methods. The Cochrane Library, Embase, Medline/Pubmed, Web of Science, and Clinical Trials databases were searched. Clinical trials of primary dental caries treated with alternative methods were included. The last search was performed on 5 August 2020. The Population, Intervention, Comparison, and Outcome (PICO) strategy was followed. Thirty-seven clinical trials were included, reporting caries removal using alternative (chemomechanical-Brix 3000, Carie-care, Carisolv and Papacarie, laser-Er:YAG (Erbium-doped Yttrium Aluminium Garnet) and Er,Cr:YSGG (Erbium, Chromium-doped Yttrium, Scandium, Gallium and Garnet), and a system combining air and sono-abrasion-Vector
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.