Evidence map›Paper›PMID 33114077›Full record

ArticleCancers2020

USP1 Regulates TAZ Protein Stability Through Ubiquitin Modifications in Breast Cancer.

Ashley Mussell, He Shen, Yanmin Chen, Michalis Mastri, Kevin H Eng, Wiam Bshara, Costa Frangou, Jianmin Zhang

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Research progress of DUB enzyme in breast cancer.Clinical and experimental medicine · 2025
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Roles of USP1 in Ewing sarcoma.Genes & cancer · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ashley MussellDepartment of Cancer Genetics & Genomics, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY 14203, USA.ORCID 0000-0001-9735-3571
He ShenDepartment of Cancer Genetics & Genomics, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY 14203, USA.
Yanmin ChenDepartment of Cancer Genetics & Genomics, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY 14203, USA.
Michalis MastriDepartment of Cancer Genetics & Genomics, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY 14203, USA.
Kevin H EngDepartment of Cancer Genetics & Genomics, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY 14203, USA.ORCID 0000-0001-5636-0812
Wiam BsharaDepartment of Pathology, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY 14263, USA.
Costa FrangouHarvard T.H. Chan School of Public Health, Molecular and Integrative Physiology Department, 665 Huntington Ave., Boston, MA 02115, USA.
Jianmin ZhangDepartment of Cancer Genetics & Genomics, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY 14203, USA.ORCID 0000-0001-7844-6254
Roswell Park Comprehensive Cancer Center · USHarvard University · US

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Dean G. Tang · 1985 to 2026
$116.6M
The role of TAZ in breast cancer initiation and progressionR01CA207504 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI ZHANG, JIANMIN · 2017 to 2021
$2.0M
NCI NIH HHS CA016056NCI NIH HHS CA207504NCI NIH HHS P30 CA016056NCI NIH HHS R01 CA207504
6 · The paper itself

Abstract

The Hippo signaling pathway is an evolutionarily conserved pathway that was initially discovered in

Indexed as

TAZtriple negative breast cancerUSP1

Identifiers

PMID33114077
PMCPMC7690829
OpenAlexW3093531500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.