Evidence map›Paper›PMID 33114064›Full record

ArticleNutrients2020

Association between Iron Status and Incident Type 2 Diabetes: A Population-Based Cohort Study.

Andrés Díaz-López, Lucía Iglesias-Vázquez, Meritxell Pallejà-Millán, Cristina Rey Reñones, Gemma Flores Mateo, Victoria Arija

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Mitochondria-associated programmed cell death in pancreatic β cell of T2DM.Apoptosis : an international journal on programmed cell death · 2026
    Review
  6. Article
  7. Review
  8. Ferroptosis-A Shared Mechanism for Parkinson's Disease and Type 2 Diabetes.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Andrés Díaz-LópezMedicine and Health Sciences Faculty, Universitat Rovira i Virgili (URV), 43201 Reus, Spain.
Lucía Iglesias-VázquezMedicine and Health Sciences Faculty, Universitat Rovira i Virgili (URV), 43201 Reus, Spain.
Meritxell Pallejà-MillánUnit of Research Support Reus-Tarragona, Jordi Gol University Institute for Primary Care Research (IDIAP), 43202 Tarragona, Spain.
Cristina Rey ReñonesUnit of Research Support Reus-Tarragona, Jordi Gol University Institute for Primary Care Research (IDIAP), 43202 Tarragona, Spain.
Gemma Flores MateoUnit of Research Support Reus-Tarragona, Jordi Gol University Institute for Primary Care Research (IDIAP), 43202 Tarragona, Spain.
Victoria ArijaMedicine and Health Sciences Faculty, Universitat Rovira i Virgili (URV), 43201 Reus, Spain.
Institut Universitari d'Investigació en Atenció Primària Jordi Gol · ESTechnological Center of Nutrition and Health · ESInstituto de Salud Carlos III · ES

Funding

Fundació la Marató de TV3 20151510
6 · The paper itself

Abstract

Type 2 diabetes poses a major public health challenge. Here, we conducted a cohort study with a large sample size to determine the association of baseline serum ferritin (SF), a marker of iron status, with incident type 2 diabetes in primary healthcare patients in Catalonia, a western Mediterranean region. A total of 206,115 patients aged 35-75 years without diabetes and with available baseline SF measurements were eligible. The variables analyzed included sociodemographic characteristics, anthropometry, lifestyle, morbidity and iron status (SF, serum iron and hemoglobin). Incident type 2 diabetes during follow-up (2006-2016) was ascertained using the International Classification of Diseases, 10th edition. Cox proportional-hazards models adjusted for multiple baseline confounders/mediators were used to estimate hazard ratios (HRs). Over a median follow-up of 8.4 years, 12,371 new cases of type 2 diabetes were diagnosed, representing an incidence rate of 7.5 cases/1000 persons/year. Since at baseline, the median SF concentration was higher in subjects who developed type 2 diabetes (107.0 µg/L vs. 60.3 µg/L;

Indexed as

Nutritional StatusAdultAgedBiomarkersDatabases, FactualDiabetes Mellitus, Type 2FemaleFerritinsHumansIncidenceIronLongitudinal StudiesMaleMiddle AgedPrimary Health CareProportional Hazards ModelsBiomarkersFerritinsIroniron statusprimary healthcareserum ferritintype 2 diabetestype 2 diabetes incidence

Identifiers

PMID33114064
PMCPMC7690731
OpenAlexW3094141695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.