Evidence map›Paper›PMID 33113975›Full record

ArticleJournal of functional biomaterials2020

Synthesis of Functional Silver Nanoparticles and Microparticles with Modifiers and Evaluation of Their Antimicrobial, Anticancer, and Antioxidant Activity.

Erum Dilshad, Mehmoona Bibi, Nadeem Ahmed Sheikh, Khairul Fikri Tamrin, Qaisar Mansoor, Qaisar Maqbool, Muhammad Nawaz

Open access · goldAbstract read
In one paragraph

Article in Journal of functional biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Article
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  4. Review
  5. Response surface methodology based optimization of keratinase fromSaudi journal of biological sciences · 2023
    Article
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  8. Review
  9. Review
  10. Non-Thermal Plasma Reduction of AgMaterials (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Erum DilshadDepartment of Bioinformatics and Biosciences, Faculty of Health and Life Sciences, Capital University of Science and Technology (CUST), 44000 Islamabad, Pakistan.
Mehmoona BibiDepartment of Bioinformatics and Biosciences, Faculty of Health and Life Sciences, Capital University of Science and Technology (CUST), 44000 Islamabad, Pakistan.
Nadeem Ahmed SheikhDepartment of Mechanical Engineering, Faculty of Engineering and Technology, International Islamic University, 44000 Islamabad, Pakistan.
Khairul Fikri TamrinDepartment of Mechanical and Manufacturing Engineering, Faculty of Engineering, University Malaysia Sarawak (UNIMAS), 94300 Kota Samarahan, Sarawak, Malaysia.
Qaisar MansoorInstitute of Biomedical and Genetic Engineering (IBGE), 44000 Islamabad, Pakistan.
Qaisar MaqboolNational Institute of Vacuum Science and Technology (NINVAST), 44000 Islamabad, Pakistan.
Muhammad NawazDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 46 Gothenburg, Sweden.
Capital University of Science and Technology · PKInstitute of Biomedical and Genetic Engineering · PKInternational Islamic University, Islamabad · PKUniversiti Malaysia Sarawak · MYUniversity of Gothenburg · SE

Funding

Adlerbertska Forskningsstiftelsen 09/2019Stiftelsen Längmanska Kulturfonden BA18-0708
6 · The paper itself

Abstract

An accumulating body of evidence reports the synthesis and biomedical applications of silver nanoparticles. However, the studies regarding the use of maleic acid and citric acid in the synthesis of nano-sized silver particles (AgNPs) and micro-sized silver particles (AgMPs) as well as their antibacterial, antifungal, and anticancer activities have not been reported. In the current study, we synthesized AgNPs and AgMPs using maleic acid and citric acid as capping agents and have characterized them by UV-Vis, energy-dispersive X-Ray spectroscopy (EDS), X-Ray diffraction (XRD), and scanning electron microscope (SEM) analysis. The capped silver particles were examined for their antimicrobial activity and cytotoxicity against bacteria, fungi, and brine shrimp. Additionally, the anticancer activity of these particles was tested against human breast and liver cancer cell lines. The free radical scavenging activity of capped silver particles was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. SEM analysis revealed a round plate-like morphology of maleic acid capped particles with an average size of 39 ± 4 nm, whereas citric acid capped particles display flower-shaped morphology with rough surfaces and an average size of 250 ± 5 nm. The uncapped AgMPs were hexagonal with 500 ± 4 nm size. EDS and XRD analysis confirmed the presence of Ag and face-centered cubic crystalline nature, respectively. Functionally, capped silver particles exhibited antibacterial activity against Gram-positive (

Indexed as

anticancerantimicrobialantioxidantcytotoxicityfunctional nanomaterialssilver microparticlessilver nanoparticlestherapeutic efficacy

Identifiers

PMID33113975
PMCPMC7711460
OpenAlexW3094621194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.