Evidence map›Paper›PMID 33113971›Full record

ArticleInternational journal of molecular sciences2020

Meta-Analysis of Transcriptome Data Detected New Potential Players in Response to Dioxin Exposure in Humans.

Evgeniya Oshchepkova, Yana Sizentsova, Daniil Wiebe, Victoria Mironova, Nikolay Kolchanov

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Environmental pro-oxidants induce altered envelope protein profiles in human keratinocytes.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Evgeniya OshchepkovaInstitute of Cytology and Genetics, 630090 Novosibirsk, Russia.
Yana SizentsovaInstitute of Cytology and Genetics, 630090 Novosibirsk, Russia.
Daniil WiebeInstitute of Cytology and Genetics, 630090 Novosibirsk, Russia.ORCID 0000-0002-0175-1127
Victoria MironovaInstitute of Cytology and Genetics, 630090 Novosibirsk, Russia.ORCID 0000-0003-3438-0147
Nikolay KolchanovInstitute of Cytology and Genetics, 630090 Novosibirsk, Russia.
Institute of Cytology and Genetics · RUNovosibirsk State University · RU

Funding

Russian Foundation for Basic Research 18-04-01130Russian Foundation for Basic Research 18-29-13040Russian State Budget 0324-2019-0040-C-01
6 · The paper itself

Abstract

Dioxins are one of the most potent anthropogenic poisons, causing systemic disorders in embryonic development and pathologies in adults. The mechanism of dioxin action requires an aryl hydrocarbon receptor (AhR), but the downstream mechanisms are not yet precisely clear. Here, we performed a meta-analysis of all available transcriptome datasets taken from human cell cultures exposed to 2,3,7,8-tetrachlorodibenzo-

Indexed as

Basic Helix-Loop-Helix ProteinsCells, CulturedComputational BiologyDatabases, GeneticDNA-Binding ProteinsE2F2 Transcription FactorGene Expression ProfilingGene Expression RegulationGene Regulatory NetworksHumansKruppel-Like Transcription FactorsMolecular Sequence AnnotationPolychlorinated DibenzodioxinsReceptors, Aryl HydrocarbonRepressor ProteinsSequence Analysis, RNAAHR protein, humanBasic Helix-Loop-Helix ProteinsCTCFL protein, humanDNA-Binding ProteinsE2F2 protein, humanE2F2 Transcription FactorKruppel-Like Transcription FactorsPolychlorinated DibenzodioxinsReceptors, Aryl HydrocarbonRepressor ProteinsZBTB14 protein, humanaryl hydrocarbon receptordioxinmeta-analysistranscription factor binding sites

Identifiers

PMID33113971
PMCPMC7672605
OpenAlexW3093884824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.