Evidence map›Paper›PMID 33113950›Full record

ReviewMolecules (Basel, Switzerland)2020

Biosynthesis and Biological Activities of Newly Discovered Amaryllidaceae Alkaloids.

Seydou Ka, Manoj Koirala, Natacha Mérindol, Isabel Desgagné-Penix

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. The Metabolic Screening in Wounded Scales ofInternational journal of molecular sciences · 2025
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  4. Article
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  6. Review
  7. Article
  8. Cripowellins PauseMolecules (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Seydou KaDepartment of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, 3351, boul. des Forges, C.P. 500, Trois-Rivières, QC G9A 5H7, Canada.ORCID 0000-0001-7697-4088
Manoj KoiralaDepartment of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, 3351, boul. des Forges, C.P. 500, Trois-Rivières, QC G9A 5H7, Canada.
Natacha MérindolDepartment of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, 3351, boul. des Forges, C.P. 500, Trois-Rivières, QC G9A 5H7, Canada.ORCID 0000-0001-6235-6465
Isabel Desgagné-PenixDepartment of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, 3351, boul. des Forges, C.P. 500, Trois-Rivières, QC G9A 5H7, Canada.ORCID 0000-0002-4355-5503
Université du Québec à Trois-Rivières · CA

Funding

Canada Research Chairs 950-232164
6 · The paper itself

Abstract

Alkaloids are an important group of specialized nitrogen metabolites with a wide range of biochemical and pharmacological effects. Since the first publication on lycorine in 1877, more than 650 alkaloids have been extracted from Amaryllidaceae bulbous plants and clustered together as the Amaryllidaceae alkaloids (AAs) family. AAs are specifically remarkable for their diverse pharmaceutical properties, as exemplified by the success of galantamine used to treat the symptoms of Alzheimer's disease. This review addresses the isolation, biological, and structure activity of AAs discovered from January 2015 to August 2020, supporting their therapeutic interest.

Indexed as

Drug DiscoveryAmaryllidaceae AlkaloidsAnimalsHumansAmaryllidaceae AlkaloidsAmaryllidaceae alkaloidsanti-cholinesteraseantiparasiticantitumorantiviralbiosynthesisspecialized metabolism

Identifiers

PMID33113950
PMCPMC7660210
OpenAlexW3094230833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.