Evidence map›Paper›PMID 33113945›Full record

ArticleNutrients2020

Differential Effect of Four-Week Feeding of Different Dietary Fats on the Accumulation of Fat and the Cholesterol and Triglyceride Contents in the Different Fat Depots.

Min Liu, David Q-H Wang, Dennis D Black, Patrick Tso

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Min LiuDepartment of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45237, USA.ORCID 0000-0003-2505-0218
David Q-H WangDepartment of Medicine and Genetics, Division of Gastroenterology and Liver Diseases, Marion Bessin Liver Research Center, Einstein-Mount Sinai Diabetes Research Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0002-5439-7651
Dennis D BlackChildren's Foundation Research Institute, Le Bonheur Children's Hospital, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.ORCID 0000-0002-1882-4310
Patrick TsoDepartment of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45237, USA.
University of Cincinnati Medical Center · USAlbert Einstein College of Medicine · USUniversity of Tennessee Health Science Center · US

Funding

Translational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STREAMSON C CHUA · 2015 to 2026
$27.7M
GPR30 and hepatic cholesterol metabolismR01DK126369 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI PESSIN, JEFFREY E. · 2020 to 2023
$1.9M
Apolipoprotein A5 and Gallstone FormationR01DK114516 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI WANG, DAVID Q · 2018 to 2021
$1.5M
GPR30 and Hepatic Cholesterol HomeostasisR01DK106249 · NIDDK · SAINT LOUIS UNIVERSITY · PI WANG, DAVID Q · 2015 to 2017
$1.0M
NIDDK NIH HHS P30 DK020541NIDDK NIH HHS R01 DK106249NIDDK NIH HHS R01 DK114516NIDDK NIH HHS R01 DK126369NIH HHS NIDDK119135 and NIDDK59630
6 · The paper itself

Abstract

The aim of the present study was to determine the effects of feeding of a high-fat diet containing different types of lipids for four weeks on the cholesterol and triglyceride contents of different fat depots and on body temperature in rats. Four groups of adult rats were fed 10% fat, containing either beef tallow, safflower oil, or fish oil, respectively, as well as a normal rodent diet with 4% fat, for four weeks. The rats on normal rodent diet consumed significantly more food and water than the rats in the other three groups. Rectal temperature increased only after four-week feeding with safflower oil fat. Increased fat deposition and adipocyte size were observed in rats fed safflower oil and beef tallow. In all fat pads of safflower oil-fed rats, cholesterol content was significantly higher than the other three groups. Feeding of beef tallow increased triglyceride depot without increasing cholesterol content. The rats fed fish oil had significantly less triglyceride and cholesterol deposition in adipose tissues than the rats fed safflower oil or beef tallow. These results clearly demonstrated the differences in fat deposition, adipocyte size and number, triglyceride and cholesterol accumulation in fat cells are dependent on the dietary lipid composition.

Indexed as

Adipose TissueAnimalsBody TemperatureCholesterolDietary FatsFatsFish OilsMaleRatsSafflower OilTriglyceridesCholesterolDietary FatsFatsFish OilsSafflower OiltallowTriglyceridescholesteroldietary lipid compositionhigh-fat diettriglyceride

Identifiers

PMID33113945
PMCPMC7690704
OpenAlexW3093992913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.