Evidence map›Paper›PMID 33113785›Full record

ArticleJournal of clinical medicine2020

Convolutional Neural Network Classifies Pathological Voice Change in Laryngeal Cancer with High Accuracy.

HyunBum Kim, Juhyeong Jeon, Yeon Jae Han, YoungHoon Joo, Jonghwan Lee, Seungchul Lee, Sun Im

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05348031 (Multimodal Analysis of Structural Voice Disorders Based on Speech and Stroboscopic Laryngoscope Video), which is not on this map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05348031 not yet recruitingnot on this mapstarted 2022, after this paper: background citation

Multimodal Analysis of Structural Voice Disorders Based on Speech and Stroboscopic Laryngoscope Video

TypeobservationalSponsorSun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityRan2022 to 2027Enrolled1ConditionsVoice Disorders
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 93 citations in OpenAlex.

  1. Pooled it
  2. Application of artificial intelligence in laryngeal lesions: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Pooled it
  3. Pooled it
  4. Review
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  7. Artificial Intelligence Assurance in Head and Neck Surgery: Now and Next.Proceedings. IEEE International Symposium on Computer-Based Medical Systems · 2025
    Article
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  9. Review
  10. Article
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  12. Article
  13. Article
  14. Artificial Intelligence in Head and Neck Surgery.Otolaryngologic clinics of North America · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

HyunBum KimDepartment of Otolaryngology-Head and Neck Surgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Juhyeong JeonDepartment of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 37673, Korea.
Yeon Jae HanDepartment of Rehabilitation Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
YoungHoon JooDepartment of Otolaryngology-Head and Neck Surgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0002-1158-0974
Jonghwan LeeDepartment of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 37673, Korea.
Seungchul LeeDepartment of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 37673, Korea.ORCID 0000-0002-1034-1410
Sun ImDepartment of Rehabilitation Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0001-8400-4911
The Catholic University of Korea Bucheon St. Mary's Hospital · KRPohang University of Science and Technology · KR

Funding

Ministry of Science and ICT, South Korea 2020R1A2C1009744.National Research Foundation of Korea 2020R1F1A1065814Postech-Catholic Biomedical Engineering Institute No. 5-2019-B0001-00119
6 · The paper itself

Abstract

Voice changes may be the earliest signs in laryngeal cancer. We investigated whether automated voice signal analysis can be used to distinguish patients with laryngeal cancer from healthy subjects. We extracted features using the software package for speech analysis in phonetics (PRAAT) and calculated the Mel-frequency cepstral coefficients (MFCCs) from voice samples of a vowel sound of /a:/. The proposed method was tested with six algorithms: support vector machine (SVM), extreme gradient boosting (XGBoost), light gradient boosted machine (LGBM), artificial neural network (ANN), one-dimensional convolutional neural network (1D-CNN) and two-dimensional convolutional neural network (2D-CNN). Their performances were evaluated in terms of accuracy, sensitivity, and specificity. The result was compared with human performance. A total of four volunteers, two of whom were trained laryngologists, rated the same files. The 1D-CNN showed the highest accuracy of 85% and sensitivity and sensitivity and specificity levels of 78% and 93%. The two laryngologists achieved accuracy of 69.9% but sensitivity levels of 44%. Automated analysis of voice signals could differentiate subjects with laryngeal cancer from those of healthy subjects with higher diagnostic properties than those performed by the four volunteers.

Indexed as

deep learninglarynx cancermachine learningvoice changevoice pathology classification

Identifiers

PMID33113785
PMCPMC7692693
OpenAlexW3094604100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.