Evidence map›Paper›PMID 33112998›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2021

Safety and patient-reported outcomes in index ablation versus repeat ablation in atrial fibrillation: insights from the German Ablation Registry.

Shinwan Kany, Johannes Brachmann, Thorsten Lewalter, Karl-Heinz Kuck, Dietrich Andresen, Stephan Willems, Ellen Hoffmann, Lars Eckardt, Dierk Thomas, Matthias Hochadel and 3 more

Abstract readMulticenter Study
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Effect of repeat catheter ablation vs. antiarrhythmic drug therapy among patients with recurrent atrial tachycardia/atrial fibrillation after atrial fibrillation catheter ablation: data from CHINA-AF registry.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  4. Article
  5. Patients' attitude towards a sham-controlled trial on pulmonary vein isolation in atrial fibrillation.Clinical research in cardiology : official journal of the German Cardiac Society · 2022
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shinwan KanyDepartment of Cardiology, University Heart and Vascular Center Hamburg-Eppendorf, Martinistraße 52, 20251, Hamburg, Germany.
Johannes BrachmannDepartment of Cardiology, Angiology and Pneumology, Coburg Hospital, Coburg, Germany.
Thorsten LewalterDepartment of Medicine-Cardiology and Intensive Care, Hospital Munich-Thalkirchen, Munich, Germany.
Karl-Heinz KuckLANS Cardiology, Hamburg, Germany.
Dietrich AndresenDepartment of Cardiology, Evangelisches Krankenhaus Hubertus, Berlin, Germany.
Stephan WillemsDepartment of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Ellen HoffmannDept. of Cardiology and Internal Intensive Care Medicine, Heart Center Munich-Bogenhausen, Munich Clinic Bogenhausen, Munich, Germany.
Lars EckardtDepartment of Cardiology (Electrophysiology), University Hospital Muenster, Muenster, Germany.
Dierk ThomasDepartment of Cardiology, University of Heidelberg, Heidelberg, Germany.
Matthias HochadelStiftung Für Herzinfarktforschung (IHF), Ludwigshafen, Germany.
Jochen SengesStiftung Für Herzinfarktforschung (IHF), Ludwigshafen, Germany.
Andreas MetznerDepartment of Cardiology, University Heart and Vascular Center Hamburg-Eppendorf, Martinistraße 52, 20251, Hamburg, Germany.
Andreas RilligDepartment of Cardiology, University Heart and Vascular Center Hamburg-Eppendorf, Martinistraße 52, 20251, Hamburg, Germany. a.rillig@uke.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary vein isolation is an established strategy for catheter ablation of atrial fibrillation (AF). However, in a significant number of patients, a repeat procedure is mandatory due to arrhythmia recurrence. In this study, we report safety data and procedural details of patients undergoing index ablation versus repeat ablation in a registry-based real-life setting.

methodsPatients from the German Ablation Registry, a prospective, multicentre registry of patients undergoing ablation between January 2007 and January 2010 were included.

resultsA total of 4155 patients were enrolled in the study. Group I (index ablation) consisted of 3377/4155 (82.1%) and group II (repeat ablation) of 738/4155 (17.9%). Patients in group I had a significantly higher ratio of paroxysmal AF (69.3% vs 61.9%, p < 0.001) and significantly less persistent AF (30.7% vs 38.1%, p < 0.001). The repeat group showed significantly lower mean RF application duration (2580 s. vs 1960, p < 0.001), less fluoroscopy time (29 min. vs. 27 min., p < 0.001), less mean dose area product (DAP) (3744 cGy × cm

conclusionRepeat catheter ablation is safe and provides a symptomatic relief comparable to index ablation. Repeat procedures are significantly shorter and use less fluoroscopy.

Indexed as

Patient Reported Outcome MeasuresRegistriesAgedAtrial FibrillationCatheter AblationFemaleFollow-Up StudiesHumansMaleMiddle AgedOperative TimeProspective StudiesPulmonary VeinsRecurrenceReoperationRisk FactorsAtrial fibrillationPatient-reported outcomesRepeat ablation

Identifiers

PMID33112998
PMCPMC8166687

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.