Evidence map›Paper›PMID 33112984›Full record

ArticleWorld journal of urology2021

Retrotrigonal muscular layer sling associated with total anatomical reconstruction in robot-assisted radical prostatectomy and early continence.

Matteo Luigi Zanoni, Fabio Grizzi, Davide Maffei, Paolo Vota, Nicola Frego, Giovanni Toia, Cinzia Mazzieri, Massimo Lazzeri, Nicolò Buffi, Giovanni Lughezzani and 5 more

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Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Matteo Luigi ZanoniDepartment of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy.
Fabio GrizziDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Milan, Pieve Emanuele, Italy.
Davide MaffeiDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Milan, Pieve Emanuele, Italy.
Paolo VotaDepartment of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy.
Nicola FregoDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Milan, Pieve Emanuele, Italy.
Giovanni ToiaDepartment of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy.
Cinzia MazzieriDepartment of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy.
Massimo LazzeriHumanitas Clinical and Research Center, IRCCS, via Manzoni 56, 20089, Rozzano, Italy.
Nicolò BuffiDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Milan, Pieve Emanuele, Italy.
Giovanni LughezzaniDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Milan, Pieve Emanuele, Italy.
Paolo CasaleHumanitas Clinical and Research Center, IRCCS, via Manzoni 56, 20089, Rozzano, Italy.
Alberto SaitaHumanitas Clinical and Research Center, IRCCS, via Manzoni 56, 20089, Rozzano, Italy.
Giorgio GuazzoniDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Milan, Pieve Emanuele, Italy.
Alberto MandressiDepartment of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy.
Gianluigi TavernaDepartment of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy. gianluigi.taverna@humanitas.it.ORCID http://orcid.org/0000-0002-5478-7692
Humanitas University · ITHumanitas Mater Domini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeUrinary continence (UC) represents the main non-oncological goal in patients undergoing robotic-assisted radical prostatectomy (RARP). To evaluate the efficacy in early UC achievement, we described a new sling technique using the retrotrigonal muscular layer (TZ sling) combined with total anatomical reconstruction (TAR). PATIENTS AND

methodsWe prospectively enrolled 407 consecutive prostate cancer (PC) patients undergoing RARP between May 2017 and January 2020. The first 250 patients underwent only TAR, while the following 157 patients TAR + TZ sling, by isolating and anchoring the retrotrigonal muscular layer to the pubic bone with 2 bilateral sutures. We defined UC as ≤ 1 pad/die, which was assessed after catheter removal at 1, 4 and 12wk using the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) score. Sling-related operative time and post-operative complications were analyzed.

resultsIn the TAR group, the UC rates at the 1, 4 and 12wk were 58%, 66% and 86%; in the TAR + TZ sling group 72%, 76% and 88%, respectively. A statistically significant difference was observed in the two groups at 1wk (p = 0.0049) and 4wk (p = 0.035) favoring the TZ sling surgical strategy. This difference in UC rates was lost at 12wk (p ≥ 0.05). No statistically significant differences in operative time, acute urinary retentions and other complication rates were observed between the two groups (p = NS).

conclusionsWe have described a new, safe, feasible modification of RARP using a sling with the retrotrigonal muscular layer associated with TAR. We have demonstrated a statistically significant improvement in early UC rate in patients who are undergoing TAR and TZ sling compared to undergoing only TAR.

Indexed as

Robotic Surgical ProceduresAgedHumansMaleMiddle AgedMuscle, SmoothProstateProstatectomyProstatic NeoplasmsRecovery of FunctionRetrospective StudiesTime FactorsUrinary IncontinenceUrinationEarly urinary continenceProstate cancerRetrotrigonal muscular layerRobotic-assisted radical prostatectomy

Identifiers

PMID33112984
OpenAlexW3095320264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.