Evidence map›Paper›PMID 33112964›Full record

ReviewDer Nervenarzt2021

[Cohort studies in child and adolescent psychiatry].

N E Holz, F Nees, A Meyer-Lindenberg, H Tost, H Hölling, T Keil, D Brandeis, M Romanos, T Banaschewski

Abstract readReview
In one paragraph

Review in Der Nervenarzt, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

N E HolzKlinik für Psychiatrie und Psychotherapie des Kindes- und Jugendalters, Zentralinstitut für seelische Gesundheit, Medizinische Fakultät Mannheim, Universität Heidelberg, J5, 68167, Mannheim, Deutschland. nathalie.holz@zi-mannheim.de.
F NeesKlinik für Psychiatrie und Psychotherapie des Kindes- und Jugendalters, Zentralinstitut für seelische Gesundheit, Medizinische Fakultät Mannheim, Universität Heidelberg, J5, 68167, Mannheim, Deutschland.
A Meyer-LindenbergKlinik für Psychiatrie und Psychotherapie, Zentralinstitut für seelische Gesundheit, Medizinische Fakultät Mannheim, Universität Heidelberg, Mannheim, Deutschland.
H TostKlinik für Psychiatrie und Psychotherapie, Zentralinstitut für seelische Gesundheit, Medizinische Fakultät Mannheim, Universität Heidelberg, Mannheim, Deutschland.
H HöllingRobert Koch-Institut, Berlin, Deutschland.
T KeilInstitut für Klinische Epidemiologie und Biometrie, Universität Würzburg, Würzburg, Deutschland.
D BrandeisKlinik für Psychiatrie und Psychotherapie des Kindes- und Jugendalters, Zentralinstitut für seelische Gesundheit, Medizinische Fakultät Mannheim, Universität Heidelberg, J5, 68167, Mannheim, Deutschland.
M RomanosZentrum für Psychische Gesundheit (ZEP), Klinik und Poliklinik für Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie, Universitätsklinikum Würzburg, Würzburg, Deutschland.
T BanaschewskiKlinik für Psychiatrie und Psychotherapie des Kindes- und Jugendalters, Zentralinstitut für seelische Gesundheit, Medizinische Fakultät Mannheim, Universität Heidelberg, J5, 68167, Mannheim, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLongitudinal cohort studies with early start and life span perspectives are increasingly recognized as being crucial to uncover developmental trajectories as well as risk and resilience factors of psychiatric disorders.

objectiveThe importance of longitudinal studies is presented and the main findings of the Mannheim study of children at risk (MARS), the adolescent brain cognitive development (ABCD), the pediatric and adolescent health survey (Kinder- und Jugendgesundheitssurvey, KiGGS) and the AIMS longitudinal European autism project (LEAP) cohort studies are described. MATERIAL AND

methodsA literature search was carried out in MEDLINE.

resultsThe MARS followed participants with psychosocial and organic risks over more than 30 years starting from birth and showed the importance of early risk factors (prenatal period up to early childhood) for neuropsychosocial development. The ABCD cohort study (start 9-10 years old) underlined the developmental significance of early socioemotional and prenatal risks as well as toxin exposure. The KiGGS cohort followed children and adolescents from age 0-17 years up to the ages of 10-28 years. Main findings underline the importance of the socioeconomic status and gender-specific effects with respect to sensitive periods for the onset and trajectories of psychiatric disorders. The AIMS cohort followed patients with and without autism spectrum disorders aged between 6 and 30 years and first results revealed small effects regarding group differences. Further, cohort studies starting prenatally along with deep phenotyping are warranted to uncover the complex etiology of mental disorders.

conclusionExisting cohort studies on early mental development have shown specific focal points. To identify general and specific risk and resilience factors for psychiatric disorders and to model trajectories, there is a need for multimodal integration of data sets.

Indexed as

Adolescent PsychiatryFamilyAdolescentAdultChildChild, PreschoolCohort StudiesFemaleHumansInfantInfant, NewbornLongitudinal StudiesPregnancyRisk FactorsYoung AdultDevelopmentNeurobiologyPsychiatric diseasesResilienceRisk

Identifiers

PMID33112964
PMCPMC7592144

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.