ArticlePloS one2020
Risks of adverse perinatal and maternal outcomes among women with hypertensive disorders of pregnancy in southwestern Uganda.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Diagnostic accuracy of NLR, MLR, PLR, SII, and SIRI for predicting major adverse maternal outcomes in preeclampsia: A systematic review.The Journal of international medical research · 2026Pooled it
- Posterior Reversible Encephalopathy Syndrome in Eclampsia: A Prospective Study of Risk Factors and Outcomes.Cureus · 2026Article
- Lived experiences of women prescribed low-dose aspirin for preeclampsia prevention: a phenomenological study.BMC pregnancy and childbirth · 2026Article
- Impact of non-communicable diseases on maternal and perinatal outcomes in a low resource setting.Maternal health, neonatology and perinatology · 2025Article
- Prediction of adverse maternal outcomes associated with preeclampsia in twin pregnancies.BMC pregnancy and childbirth · 2025Article
- Comorbidities among women presenting for obstetric care in Uganda.BMC pregnancy and childbirth · 2025Article
- Magnitude and determinants of adverse perinatal outcomes of pregnancies complicated with preeclampsia and eclampsia at a teaching hospital in the Tigray region of Ethiopia.Scientific reports · 2025Article
- Barriers and enablers of early health-seeking behaviour among women with preeclampsia and eclampsia: a qualitative study at a National referral hospital in Uganda.BMC pregnancy and childbirth · 2025Article
- Haemodynamic changes from prepregnancy to very early pregnancy among women planning to conceive in Southwestern Uganda.Journal of hypertension · 2025Article
- Predicting complications in hypertensive disorders of pregnancy: external validation of a prognostic model for adverse perinatal outcomes.AJOG global reports · 2025Article
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- Global burden, trends and inequalities of maternal hypertensive disorders among reproductive-age women of advanced maternal age, 1990-2021: a population-based study.Frontiers in global women's health · 2025Article
- Article
- Association Between Short Birth Interval and Immediate Adverse Perinatal Outcomes Among Women Delivering at a Tertiary Hospital in South-Western Uganda.International journal of women's health · 2025Article
- Article
- HELLP syndrome and associated factors among pregnant women with preeclampsia/eclampsia at a referral hospital in southwestern Uganda: a cross-sectional study.BMC pregnancy and childbirth · 2024Article
- Association between late pregnancy prehypertension and adverse outcomes among newborns of women delivered at a tertiary hospital in Eastern Uganda: a prospective cohort study.BMC pregnancy and childbirth · 2024Article
- Maternal near miss as a predictor of adverse perinatal outcomes: findings from a prospective cohort study in southwestern Uganda.BMC pregnancy and childbirth · 2024Article
- Article
- Prevalence and Factors Associated With Abnormal Cerebroplacental Ratio Among Women With Hypertensive Disorders of Pregnancy at a Tertiary Referral Hospital in Southwestern Uganda.Journal of pregnancy · 2024Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
Abstract
introductionHypertensive disorders of pregnancy (HDP) are a leading cause of global perinatal (fetal and neonatal) and maternal morbidity and mortality. We sought to describe HDP and determine the magnitude and risk factors for adverse perinatal and maternal outcomes among women with HDP in southwestern Uganda.
methodsWe prospectively enrolled pregnant women admitted for delivery and diagnosed with HDP at a tertiary referral hospital in southwestern Uganda from January 2019 to November 2019, excluding women with pre-existing hypertension. The participants were observed and adverse perinatal and maternal outcomes were documented. We used multivariable logistic regression models to determine independent risk factors associated with adverse perinatal and maternal outcomes.
resultsA total of 103 pregnant women with a new-onset HDP were enrolled. Almost all women, 93.2% (n = 96) had either pre-eclampsia with severe features or eclampsia. The majority, 58% (n = 60) of the participants had an adverse perinatal outcome (36.9% admitted to the neonatal intensive care unit (ICU), 20.3% stillbirths, and 1.1% neonatal deaths). Fewer participants, 19.4% (n = 20) had an adverse maternal outcome HELLP syndrome (7.8%), ICU admission (3%), and postpartum hemorrhage (3%). In adjusted analyses, gestational age of < 34 weeks at delivery and birth weight <2.5kg were independent risk factors for adverse perinatal outcomes while referral from another health facility and eclampsia were independent risk factors for adverse maternal outcomes.
conclusionAmong women with HDP at our institution, majority had preeclampsia with severe symptoms or eclampsia and an unacceptably high rate of adverse perinatal and maternal outcomes; over a fifth of the mothers experiencing stillbirth. This calls for improved antenatal surveillance of women with HDP and in particular improved neonatal and maternal critical care expertise at delivering facilities. Earlier detection and referral, as well as improvement in initial management at lower level health units and on arrival at the referral site is imperative.
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