Evidence map›Paper›PMID 33112892›Full record

Observational studyPloS one2020

Investigating the association between ethnicity and health outcomes in SARS-CoV-2 in a London secondary care population.

Aatish Patel, Ahmed Abdulaal, David Ariyanayagam, Kieran Killington, Sarah J Denny, Nabeela Mughal, Stephen Hughes, Nupur Goel, Gary W Davies, Luke S P Moore and 1 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Kidney implications of SARS-CoV2 infection in children.Pediatric nephrology (Berlin, Germany) · 2022
    Review
  6. Review
  7. Article
  8. Article
  9. Increased severity in SARS-CoV-2 infection of minorities in Spain.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2021
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Aatish PatelChelsea and Westminster NHS Foundation Trust, London, United Kingdom.ORCID 0000-0002-2503-2602
Ahmed AbdulaalChelsea and Westminster NHS Foundation Trust, London, United Kingdom.
David AriyanayagamImperial College London, Kensington, London, United Kingdom.
Kieran KillingtonChelsea and Westminster NHS Foundation Trust, London, United Kingdom.
Sarah J DennyChelsea and Westminster NHS Foundation Trust, London, United Kingdom.
Nabeela MughalChelsea and Westminster NHS Foundation Trust, London, United Kingdom.
Stephen HughesChelsea and Westminster NHS Foundation Trust, London, United Kingdom.
Nupur GoelChelsea and Westminster NHS Foundation Trust, London, United Kingdom.
Gary W DaviesChelsea and Westminster NHS Foundation Trust, London, United Kingdom.ORCID 0000-0001-9945-4616
Luke S P MooreChelsea and Westminster NHS Foundation Trust, London, United Kingdom.ORCID 0000-0001-7095-7922
Esmita CharaniImperial College London, NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Hammersmith Campus, London, United Kingdom.ORCID 0000-0002-5938-1202
Chelsea and Westminster Hospital NHS Foundation Trust · GBImperial College Healthcare NHS Trust · GBImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlack, Asian and minority ethnic (BAME) populations are emerging as a vulnerable group in the severe acute respiratory syndrome coronavirus disease (SARS-CoV-2) pandemic. We investigated the relationship between ethnicity and health outcomes in SARS-CoV-2. METHODS AND

findingsWe conducted a retrospective, observational analysis of SARS-CoV-2 patients across two London teaching hospitals during March 1 -April 30, 2020. Routinely collected clinical data were extracted and analysed for 645 patients who met the study inclusion criteria. Within this hospitalised cohort, the BAME population were younger relative to the white population (61.70 years, 95% CI 59.70-63.73 versus 69.3 years, 95% CI 67.17-71.43, p<0.001). When adjusted for age, sex and comorbidity, ethnicity was not a predictor for ICU admission. The mean age at death was lower in the BAME population compared to the white population (71.44 years, 95% CI 69.90-72.90 versus, 77.40 years, 95% CI 76.1-78.70 respectively, p<0.001). When adjusted for age, sex and comorbidities, Asian patients had higher odds of death (OR 1.99: 95% CI 1.22-3.25, p<0.006).

conclusionsBAME patients were more likely to be admitted younger, and to die at a younger age with SARS-CoV-2. Within the BAME cohort, Asian patients were more likely to die but despite this, there was no difference in rates of admission to ICU. The reasons for these disparities are not fully understood and need to be addressed. Investigating ethnicity as a clinical risk factor remains a high public health priority. Studies that consider ethnicity as part of the wider socio-cultural determinant of health are urgently needed.

Indexed as

BetacoronavirusPandemicsAdolescentAdultAgedAged, 80 and overAsian PeopleBlack PeopleChildChild, PreschoolCoronavirus InfectionsCOVID-19EthnicityFemaleHospital MortalityHospitals, Teaching

Identifiers

PMID33112892
PMCPMC7592846
OpenAlexW3097835883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.