SynthesisPloS one2020
Evidence for the effects of prehabilitation before ACL-reconstruction on return to sport-related and self-reported knee function: A systematic review.
Synthesis in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The majority of elite and professional athletes return to the preinjury level of activity after anterior cruciate ligament reconstruction: A systematic review and meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Pooled it
- Suture tape augmentation in the management of anterior cruciate ligament ruptures: a systematic review and meta-analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025Pooled it
- Effects of Prehabilitation With Advanced Technologies in Patients With Musculoskeletal Diseases Waiting for Surgery: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2024Pooled it
- ACL Reconstruction: Which Additional Physiotherapy Interventions Improve Early-Stage Rehabilitation? A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Effectiveness of exercise prehabilitation before anterior cruciate ligament reconstruction on functional outcomes - a single-blinded randomized controlled trial.Scientific reports · 2026Trial
- Fear of Reinjury Following Surgical and Nonsurgical Management of Anterior Cruciate Ligament Injury: An Exploratory Analysis of the NACOX Multicenter Longitudinal Cohort Study.Physical therapy · 2022Trial
- Mobile health-based home rehabilitation education improving early outcomes after anterior cruciate ligament reconstruction: A randomized controlled clinical trial.Frontiers in public health · 2022Trial
- No association between anterior cruciate ligament reconstruction using hamstring autograft and knee flexion strength deficits at 4 months on seated isokinetic testing at 180°/s in adolescents.Journal of experimental orthopaedics · 2026Article
- Role of Prehabilitation in Improving Outcomes after Anterior Cruciate Ligament Reconstruction.Journal of orthopaedic case reports · 2026Article
- Preoperative prehabilitation in adults: A concept analysis.International journal of nursing studies advances · 2026Review
- Evidence Summary for Early-Stage Rehabilitation After Anterior Cruciate Ligament Reconstruction.Journal of multidisciplinary healthcare · 2026Review
- Evolution of pre- and post-operative balance characteristics in patients undergoing anterior cruciate ligament reconstruction: implications for rehabilitation.Frontiers in bioengineering and biotechnology · 2026Article
- Blood Flow Restriction Training Prior to and After Anterior Cruciate Ligament Reconstruction: A Scoping Review.Journal of functional morphology and kinesiology · 2025Review
- Risk Factors for Arthrofibrosis in Schenck KD 3 and 4 Multiligament Knee Injury Patients.Orthopaedic journal of sports medicine · 2025Article
- Five Weeks of Whole-body Vibration in Prehabilitation for Knee Function Following Anterior Cruciate Ligament Reconstruction: A Single-blinded Randomized Controlled Trial.Sports medicine - open · 2025Article
- Pediatric Sports: The Mental Health and Psychological Impact of Sport and Injury.Journal of clinical medicine · 2025Review
- Isokinetic Testing After Anterior Cruciate Ligament Injury Showed a Greater Hamstrings/Quadriceps Ratio at 240°/S Over 6 Months From Injury but No Difference of Limb Symmetry Index.Arthroscopy, sports medicine, and rehabilitation · 2025Article
- Persistent cognitive deficits in ACL-injured athletes despite of rehabilitation: an observational longitudinal study.Frontiers in sports and active living · 2025Article
- Postoperative anterior cruciate ligament rehabilitation: A survey in Gauteng, South Africa.The South African journal of physiotherapy · 2025Article
- The Effect of Physiotherapy on Arthrogenic Muscle Inhibition After ACL Injury or Reconstruction: A Systematic Review.Life (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designSystematic review. BACKGROUND AND
objectivesPreoperative neuromuscular function is predictive for knee function and return to sports (RTS) after reconstruction of the anterior cruciate ligament (ACL). The aim of this review was to examine the potential benefits of prehabilitation on pre-/postoperative objective, self-reported and RTS-specific outcomes.
methodsA systematic search was conducted within three databases. From the 1.071 studies screened, two randomized control trials (RCTs), two control trials (CTs) and two cohort studies (CS) met the inclusion criteria. Methodological quality rating adopted the PEDro- (RCT, CT) or Newcastle-Ottawa-Scale (CS). RESULTS AND
conclusionsMethodological quality of the included studies was moderate (PEDro score: 6.5 ± 1.7; range 4 to 9). Two studies reported higher increases of the maximal quadriceps torque from baseline to pre-reconstruction: one study in the limb symmetry index (LSI), and one in both legs of the prehabilitation group compared to the controls. At 12-weeks post-reconstruction, one study (from two) indicated that the prehabilitation group had a lesser post-operative decline in the single-leg-hop for distance LSI (clinically meaningful). Similar findings were found in terms of quadriceps strength LSI (one study). At both pre-reconstruction (three studies) and two-year post-surgery (two studies), the prehabilitation groups reached significantly higher self-reported knee function (clinically meaningful) than the controls. RTS tended to be faster (one study). At two years post-surgery, RTS rates (one study) were higher in the prehabilitation groups. The results provide evidence for the relevance of prehabilitation prior to ACL-reconstruction to improve neuromuscular and self-reported knee function as well as RTS. More high quality confirmatory RCTs are warranted. REGISTRATION NUMBER: PROSPERO 2017: CRD42017065491.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.