Evidence map›Paper›PMID 33112648›Full record

ReviewThe British journal of radiology2021

Abdominal immune-related adverse events: detection on ultrasonography, CT, MRI and 18F-Fluorodeoxyglucose positron emission tomography.

Mark A Anderson, Vikram Kurra, William Bradley, Aoife Kilcoyne, Amirkasra Mojtahed, Susanna I Lee

Open access · bronzeAbstract readReview
In one paragraph

Review in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. IsCancers · 2024
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Diagnostic impact ofClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Article
  12. MRI techniques for immunotherapy monitoring.Journal for immunotherapy of cancer · 2022
    Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mark A AndersonDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0002-6144-9093
Vikram KurraDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
William BradleyDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Aoife KilcoyneDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Amirkasra MojtahedDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Susanna I LeeDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Harvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune checkpoint inhibitor and chimeric antigen receptor T-cell therapies are associated with a unique spectrum of complications termed immune-related adverse events (irAEs). The abdomen is the most frequent site of severe irAEs that require hospitalization with life-threatening consequences. Most abdominal irAEs such as enterocolitis, hepatitis, cholangiopathy, cholecystitis, pancreatitis, adrenalitis, and sarcoid-like reaction are initially detected on imaging such as ultrasonography (US), CT, MRI and fusion 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)-CT during routine surveillance of cancer therapy. Early recognition and diagnosis of irAEs and immediate management with cessation of immune modulator cancer therapy and institution of immunosuppressive therapy are necessary to avert morbidity and mortality. Diagnosis of irAEs is confirmed by tissue sampling or by follow-up imaging demonstrating resolution. Abdominal radiologists reviewing imaging on patients being treated with anti-cancer immunomodulators should be familiar with the imaging manifestations of irAEs.

Indexed as

Digestive System DiseasesFluorodeoxyglucose F18HumansImmunotherapyMagnetic Resonance ImagingNeoplasmsPositron Emission Tomography Computed TomographyRadiopharmaceuticalsTomography, X-Ray ComputedUltrasonographyFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID33112648
PMCPMC7934307
OpenAlexW3096065468

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.