Evidence map›Paper›PMID 33112235›Full record

ArticleeLife2020

Functional exploration of heterotrimeric kinesin-II in IFT and ciliary length control in

Shufen Li, Kirsty Y Wan, Wei Chen, Hui Tao, Xin Liang, Junmin Pan

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Regulation of kinesin-2 motility by its β-hairpin motif.Nature structural & molecular biology · 2025
    Article
  2. Article
  3. Article
  4. Frontiers in cell and developmental biology · 2024
    Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Shufen LiMOE Key Laboratory of Protein Sciences, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Kirsty Y WanLiving Systems Institute, University of Exeter, Exeter, United Kingdom.ORCID 0000-0002-0291-328X
Wei ChenMOE Key Laboratory of Protein Sciences, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.ORCID 0000-0001-7454-3882
Hui TaoMOE Key Laboratory of Protein Sciences, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Xin LiangMOE Key Laboratory of Protein Sciences, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.ORCID 0000-0001-7915-8094
Junmin PanMOE Key Laboratory of Protein Sciences, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.ORCID 0000-0003-1242-3791
Center for Life Sciences · CNQingdao National Laboratory for Marine Science and Technology · CNUniversity of Exeter · GB

Funding

Ministry of Science and Technology of the People's Republic of China 2017YFA0503500Ministry of Science and Technology of the People's Republic of China 2018YFA0902500National Natural Science Foundation of China 31671387National Natural Science Foundation of China 31922018National Natural Science Foundation of China 31972888National Natural Science Foundation of China 31991191Springboard Award from the Academy of Medical Sciences and Global Challenges Research Fund SBF003\1160Springboard Award from the Academy of Medical Sciences and Global Challenges Research Fund Research Fund SBF003\1160
6 · The paper itself

Abstract

Heterodimeric motor organization of kinesin-II is essential for its function in anterograde IFT in ciliogenesis. However, the underlying mechanism is not well understood. In addition, the anterograde IFT velocity varies significantly in different organisms, but how this velocity affects ciliary length is not clear. We show that in

Indexed as

Algal ProteinsChlamydomonas reinhardtiiCiliaKinesinsAlgal Proteinskinesin-IIKinesinsC. eleganscell biologychlamydomonas reinhardtiiciliaciliary lengthflagellaintraflagellar transportKinesin-II

Identifiers

PMID33112235
PMCPMC7652414
OpenAlexW3097679100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.