Evidence map›Paper›PMID 33112226›Full record

ArticleMicrobial genomics2020

Whole-genome epidemiology links phage-mediated acquisition of a virulence gene to the clonal expansion of a pandemic

Eleonora Tassinari, Matt Bawn, Gaetan Thilliez, Oliver Charity, Luke Acton, Mark Kirkwood, Liljana Petrovska, Timothy Dallman, Catherine M Burgess, Neil Hall and 2 more

Open access · goldAbstract read
In one paragraph

Article in Microbial genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

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  16. PeerJ · 2022
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  17. Antibiotics (Basel, Switzerland) · 2021
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  18. Review
  19. Colistin Resistance in Monophasic Isolates ofFrontiers in microbiology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Eleonora TassinariQuadram Institute Bioscience, Norwich Research Park, Norwich, UK.
Matt BawnQuadram Institute Bioscience, Norwich Research Park, Norwich, UK.
Gaetan ThilliezQuadram Institute Bioscience, Norwich Research Park, Norwich, UK.
Oliver CharityQuadram Institute Bioscience, Norwich Research Park, Norwich, UK.
Luke ActonQuadram Institute Bioscience, Norwich Research Park, Norwich, UK.
Mark KirkwoodQuadram Institute Bioscience, Norwich Research Park, Norwich, UK.
Liljana PetrovskaAnimal and Plant Health Agency, Addlestone, UK.
Timothy DallmanGastrointestinal Bacteria Reference Unit, National Infection Service, Public Health England, London, UK.
Catherine M BurgessTeagasc Food Research Centre, Ashtown, Dublin 15, Ireland.
Neil HallEarlham Institute, Norwich Research Park, Norwich, UK.
Geraldine DuffyTeagasc Food Research Centre, Ashtown, Dublin 15, Ireland.
Robert A KingsleyQuadram Institute Bioscience, Norwich Research Park, Norwich, UK.
Norwich Research Park · GBTeagasc - The Irish Agriculture and Food Development Authority · IEAnimal and Plant Health Agency · GBPublic Health England · GBUniversity of East Anglia · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M025489/1Biotechnology and Biological Sciences Research Council BB/N007964/1Biotechnology and Biological Sciences Research Council BB/R012504/1Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10348Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10349
6 · The paper itself

Abstract

Epidemic and pandemic clones of bacterial pathogens with distinct characteristics continually emerge, replacing those previously dominant through mechanisms that remain poorly characterized. Here, whole-genome-sequencing-powered epidemiology linked horizontal transfer of a virulence gene,

Indexed as

AnimalsBacterial ProteinsBacteriophagesClonal EvolutionGenome, BacterialGuanine Nucleotide Exchange FactorsSalmonella Infections, AnimalSalmonella typhimuriumSwineSwine DiseasesVirulenceVirulence FactorsWhole Genome SequencingBacterial ProteinsGuanine Nucleotide Exchange FactorsSopE protein, SalmonellaVirulence FactorsepidemicevolutionphylogenomicsSalmonellasopE

Identifiers

PMID33112226
PMCPMC7725340
OpenAlexW3094657818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.