Evidence map›Paper›PMID 33112159›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2021

Expression of the regulated isoform of the electrogenic Na

Maria-Gabriela Colmenares Aguilar, Amelia Mazzone, Seth T Eisenman, Peter R Strege, Cheryl E Bernard, Heather L Holmes, Michael F Romero, Gianrico Farrugia, Simon J Gibbons

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. The role of NaPflugers Archiv : European journal of physiology · 2024
    Review
  2. Article
  3. Bicarbonate ion transport by the electrogenic NaNeurogastroenterology and motility · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Maria-Gabriela Colmenares AguilarEnteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
Amelia MazzoneEnteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
Seth T EisenmanEnteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
Peter R StregeEnteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
Cheryl E BernardEnteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
Heather L HolmesPhysiology and Biomedical Engineering, Nephrology and Hypertension, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.
Michael F RomeroPhysiology and Biomedical Engineering, Nephrology and Hypertension, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.
Gianrico FarrugiaEnteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0003-3473-5235
Simon J GibbonsEnteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0001-5311-5993
Mayo Clinic · US

Funding

PILOT AND FEASIBILTY PROGRAMP30DK084567 · NIDDK · MAYO CLINIC ROCHESTER · PI Nicholas F. LaRusso · 2009 to 2026
$22.2M
CALCIUM DYNAMICS IN INTERSTITIAL CELLS OF CAJALR01DK057061 · NIDDK · MAYO CLINIC ROCHESTER · PI GIANRICO FARRUGIA, Tamas Ordog · 2000 to 2026
$8.2M
NIDDK NIH HHS P30 DK084567NIDDK NIH HHS R01 DK057061
6 · The paper itself

Abstract

Interstitial cells of Cajal (ICCs) generate electrical slow waves, which are required for normal gastrointestinal motility. The mechanisms for generation of normal pacemaking are not fully understood. Normal gastrointestinal contractility

Indexed as

AdultAgedAnimalsHumansInterstitial Cells of CajalIntestine, SmallMice, TransgenicMiddle AgedMuscle, SmoothOocytesRibosomal ProteinsRNA-Binding ProteinsSodiumSodium-Bicarbonate SymportersSymportersRibosomal ProteinsRNA-Binding ProteinsSLC4A4 protein, humanSodiumSodium-Bicarbonate SymportersSymportersbicarbonate transport in gastrointestinal motilityhuman small intestine“IP3-receptor binding protein released by IP3” (IRBIT)-regulated NBCe1-B/CRibotag mouseSlc4a4

Identifiers

PMID33112159
PMCPMC8112189
OpenAlexW3096937222

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.