ArticleAnnals of biomedical engineering2021
Mechanobiology of Bone Consolidation During Distraction Osteogenesis: Bone Lengthening Vs. Bone Transport.
Article in Annals of biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 18 citations in OpenAlex.
- Evaluation of the extent of bone healing in mandibular distraction osteogenesis using pre-operative and post-operative imaging pixel value ratio: a cohort study.Quantitative imaging in medicine and surgery · 2026Article
- Initial fracture gap distance as a potential quantitative predictor for atlas fracture nonunion: A preliminary retrospective analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- [Free latissimus dorsi myocutaneous flap transplantation combined with external fixation for bone and soft tissue defects around knee joint].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Article
- Measurement of the dynamic axial load-share ratio in vivo could indicate sufficient callus healing in external fixators.BMC musculoskeletal disorders · 2025Article
- Bone regeneration during osteoporosis: a translationalFrontiers in bioengineering and biotechnology · 2025Article
- Risk of fragility fracture is aggravated during bone regeneration processes in osteoporotic sheep.PloS one · 2025Article
- Outcome of limb lengthening as a treatment for shortening following successful replantation of traumatic leg amputation: experience with 21 patients.Frontiers in surgery · 2025Article
- [Research progress in repair and reconstruction of tumor-related bone defects in proximal femur].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024Review
- Article
- On the influence of structural and chemical properties on the elastic modulus of woven bone under healing.Frontiers in bioengineering and biotechnology · 2024Article
- Biomechanical gait analysis in sheep: kinematic parameters.Frontiers in bioengineering and biotechnology · 2024Article
- Article
- Time-Dependent Collagen Fibered Structure in the Early Distraction Callus: Imaging Characterization and Mathematical Modeling.Annals of biomedical engineering · 2022Article
- The progress in quantitative evaluation of callus during distraction osteogenesis.BMC musculoskeletal disorders · 2022Review
- Evaluation of complications associated with bifocal bone transport as treatment for either proximal, intermediate or distal femoral defects caused by infection: outcome analysis of 76 patients.BMC musculoskeletal disorders · 2022Article
- Mechanobiology of Bone Consolidation During Distraction Osteogenesis: Bone Lengthening Vs. Bone Transport.Annals of biomedical engineering · 2021Article
- Mechanobiology of Bone Consolidation During Distraction Osteogenesis: Bone Lengthening Vs. Bone Transport.Annals of biomedical engineering · 2021Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Bone lengthening and bone transport are regeneration processes that commonly rely on distraction osteogenesis, a widely accepted surgical procedure to deal with numerous bony pathologies. Despite the extensive study in the literature of the influence of biomechanical factors, a lack of knowledge about their mechanobiological differences prevents a clinical particularization. Bone lengthening treatments were performed on sheep metatarsus by reproducing the surgical and biomechanical protocol of previous bone transport experiments. Several in vivo monitoring techniques were employed to build an exhaustive comparison: gait analysis, radiographic and CT assessment, force measures through the fixation, or mechanical characterization of the new tissue. A significant initial loss of the bearing capacity, quantified by the ground reaction forces and the limb contact time with the ground, is suffered by the bone lengthening specimens. The potential effects of this anomaly on the musculoskeletal force distribution and the evolution of the bone callus elastic modulus over time are also analyzed. Imaging techniques also seem to reveal lower bone volume in the bone lengthening callus than in the bone transport one, but an equivalent mineralization rate. The simultaneous quantification of biological and mechanical parameters provides valuable information for the daily clinical routine and numerical tools development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.