Evidence map›Paper›PMID 33111647›Full record

Trial reportJournal of ethnicity in substance abuse

Ethnoracial differences in treatment-seeking veterans with substance use disorders and co-occurring PTSD: Presenting characteristics and response to integrated exposure-based treatment.

Delisa G Brown, Julianne C Flanagan, Amber Jarnecke, Therese K Killeen, Sudie E Back

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of ethnicity in substance abuse. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Delisa G BrownMedical University of South Carolina, Charleston, South Carolina.
Julianne C FlanaganMedical University of South Carolina, Charleston, South Carolina.
Amber JarneckeMedical University of South Carolina, Charleston, South Carolina.
Therese K KilleenMedical University of South Carolina, Charleston, South Carolina.
Sudie E BackMedical University of South Carolina, Charleston, South Carolina.
Medical University of South Carolina · US

Funding

Vocational Training for Drug Dependent WomenP50DA016511 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2002 to 2017
$14.5M
Drug Abuse Research Training (DART) ProgramR25DA020537 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KATHLEEN T. BRADY, Sudie E Back · 2006 to 2026
$6.3M
Randomized Controlled Trial of N-acetylcysteine for Alcohol Use Disorder and Comorbid PTSDR01AA025086 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BACK, SUDIE E, GRAY, KEVIN M · 2016 to 2020
$3.1M
Integrated Treatment of OEF/OIF Veterans with PTSD and Substance Use DisordersR01DA030143 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BACK, SUDIE E · 2010 to 2014
$1.6M
Identifying the neurobehavioral signature of individuals with AUD and comorbid PTSDK23AA027307 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI JARNECKE, AMBER · 2019 to 2023
$1.0M
Integrating Neurobiology and Neuroimaging into Research on Addiction and PTSDK02DA039229 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BACK, SUDIE E · 2015 to 2019
$779k
Effects of Oxytocin on Alcohol Craving and Intimate Partner AggressionK23AA023845 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI FLANAGAN, JULIANNE CHRISTINA · 2016 to 2019
$774k
NIAAA NIH HHS K23 AA023845NIAAA NIH HHS K23 AA027307NIAAA NIH HHS R01 AA025086NIDA NIH HHS K02 DA039229NIDA NIH HHS P50 DA016511NIDA NIH HHS R01 DA030143NIDA NIH HHS R25 DA020537
6 · The paper itself

Abstract

objectiveSubstance use disorders (SUD) and posttraumatic stress disorder (PTSD) frequently co-occur. While previous research has examined ethnoracial differences among individuals with either SUD or PTSD, little research to date has focused on individuals with co-occurring SUD/PTSD. The current study addresses this gap in the literature.

methodParticipants were 79 military veterans (91% male; 38% African American [AA] and 62% White) with current SUD/PTSD who were randomized to receive Concurrent Treatment of PTSD and Substance Use Disorders using Prolonged Exposure (COPE) or Relapse Prevention (RP). Primary outcomes included substance use and self-reported and clinician-rated PTSD symptoms.

resultsAt baseline, AA participants were significantly older, reported greater substance and alcohol use, and tended to report higher PTSD severity than White participants. AA participants evidenced greater decreases in substance and alcohol use during treatment, but greater increases in substance and alcohol use during follow-up as compared to White participants. All participants decreased alcohol consumption during treatment; however, AA participants in the COPE condition and White participants in the RP condition evidenced the steepest decreases in average number of drinks per drinking day (DDD) during treatment. Additionally, White participants receiving RP reported greater increases in DDD during follow-up compared to AA participants.

conclusionOverall, integrated treatment for co-occurring SUD/PTSD was effective for both AA and White participants; however, some important differences emerged by ethnoracial group. Findings suggest that greater attention to race and ethnicity is warranted to better understand the needs of diverse patients with SUD/PTSD and to optimize treatment outcomes.

Indexed as

Stress Disorders, Post-TraumaticSubstance-Related DisordersVeteransAlcohol DrinkingComorbidityFemaleHumansMaleTreatment Outcomeethnoracialhealth disparitiesPTSDraceSubstance use disorderstrauma

Identifiers

PMID33111647
PMCPMC8079537
OpenAlexW3096060902

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.