Evidence map›Paper›PMID 33111628›Full record

SynthesisAmerican journal of men's health

Efficacy of Aspirin for Vasculogenic Erectile Dysfunction in Men: A Meta-Analysis of Randomized Control Trials.

Muhammad Irfan, Shaiful Bahari Ismail, Norhayati Mohd Noor, Nik Hazlina Nik Hussain

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in American journal of men's health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cardiometabolic Disorder and Erectile Dysfunction.Cell biochemistry and biophysics · 2024
    Review
  5. Observational
  6. Article
  7. Acetylsalicylic Acid and Mood Disorders: A Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Muhammad IrfanWomen's Health Development Unit, Universiti Sains Malaysia, Kelantan, Malaysia.ORCID 0000-0002-5308-2359
Shaiful Bahari IsmailDepartment of Family Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
Norhayati Mohd NoorDepartment of Family Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
Nik Hazlina Nik HussainWomen's Health Development Unit, Universiti Sains Malaysia, Kelantan, Malaysia.ORCID 0000-0002-9476-062X
Universiti Sains Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the major causes of erectile dysfunction (ED) is an endothelial vascular disorder. This meta-analysis is performed to determine the efficacy of aspirin on erectile function in men with vasculogenic ED. For this purpose, CENTRAL, MEDLINE, and reference lists of articles up to November 2019 were searched. Randomized controlled trials (RCTs) were selected that compared aspirin with placebo in men of any ethnicity with vasculogenic ED. A total of 58 trials were retrieved. Finally, two trials of 214 men fulfilled our selection criteria. High selection and detection bias were identified for one trial. The participants showed a significant improvement in erectile function when they took aspirin (mean difference: 5.14, 95% CI [3.89, 6.40], and I

Indexed as

Randomized Controlled Trials as TopicAspirinErectile DysfunctionHumansMalePenile ErectionVascular DiseasesAspirinAspirincardiovascular diseasesendothelial dysfunctionerectile dysfunctionnitric oxide

Identifiers

PMID33111628
PMCPMC7607788
OpenAlexW3097837018

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.