Evidence map›Paper›PMID 33111593›Full record

ArticleJournal of child neurology2021

Novel Neurotechnological Interventions for Pediatric Drug-Resistant Epilepsy: Physician Perspectives.

Patrick J McDonald, Viorica Hrincu, Mary B Connolly, Mark J Harrison, George M Ibrahim, Robert P Naftel, Winston Chiong, Farhad Udwadia, Judy Illes

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Journal of child neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Ethical Considerations for Discrete Choice Experiments with Caregivers.Journal of empirical research on human research ethics : JERHRE · 2022
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Patrick J McDonald8166University of British Columbia, Division of Neurology, Department of Medicine, Vancouver, British Columbia, Canada.
Viorica Hrincu8166University of British Columbia, Division of Neurology, Department of Medicine, Vancouver, British Columbia, Canada.
Mary B ConnollyDepartment of Pediatrics, Division of Neurology, BC Children's Hospital, Vancouver, 8166British Columbia, Canada.
Mark J Harrison8166University of British Columbia, Vancouver, British Columbia, Canada.
George M IbrahimDivision of Neurosurgery, 483367Hospital for Sick Children and Toronto Western Hospital, Toronto, Ontario, Canada.
Robert P NaftelDepartment of Neurosurgery, 12328Vanderbilt University Medical Center, Nashville, TN, USA.
Winston ChiongWeill Institute for Neurosciences, Department of Neurology, Memory and Aging Center, 550067University of California San Francisco, San Francisco, CA, USA.
Farhad Udwadia8166University of British Columbia, Division of Neurology, Department of Medicine, Vancouver, British Columbia, Canada.
Judy Illes8166University of British Columbia, Division of Neurology, Department of Medicine, Vancouver, British Columbia, Canada.ORCID 0000-0002-4791-8084
University of British Columbia · CABC Children's Hospital · CAToronto Western Hospital · CAUniversity of California, San Francisco · USVanderbilt University Medical Center · US

Funding

Achieving ethical integration in the development of novel neurotechnologiesR01MH114860 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHIONG, WINSTON, DOHAN, DANIEL P. · 2017 to 2020
$2.0M
Informing Choice for Neurotechnological Innovation in Pediatric Epilepsy SurgeryRF1MH117805 · NIMH · UNIVERSITY OF BRITISH COLUMBIA · PI ILLES, JUDY, MCDONALD, PATRICK · 2018 to 2018
$534k
NIMH NIH HHS R01 MH114860NIMH NIH HHS RF1 MH117805
6 · The paper itself

Abstract

This qualitative study investigated factors that guide physicians' choices for minimally invasive and neuromodulatory interventions as alternatives to conventional surgery or medical management for pediatric drug-resistant epilepsy. North American physicians were recruited to one of 4 focus groups at national conferences. Discussions were analyzed using qualitative content analysis. A pragmatic neuroethics framework was applied to interpret results. Discussions revealed 2 major thematic branches: (1) clinical decision making and (2) ethical considerations. Under clinical decision making, physicians emphasized scientific evidence and patient candidacy when assessing neurotechnologies for patients. Ongoing seizures without intervention was important for safety and neurodevelopment. Under ethical considerations, resource allocation, among other financial considerations for technology adoption, were considerable sources of pressure on decision making. Access to neurotechnology was a salient theme differentiating Canadian and American contexts. When assessing novel neurotechnological interventions for pediatric drug-resistant epilepsy, physicians balance clinical and ethical factors to guide decision making and best practice.

Indexed as

CanadaClinical Decision-MakingElectric Stimulation TherapyEpilepsyHumansPhysiciansPractice Patterns, Physicians'Qualitative ResearchRadiosurgeryUltrasonic TherapyUnited Statesepilepsyethicsneurosurgerypediatrictreatment

Identifiers

PMID33111593
PMCPMC7855396
OpenAlexW3096401626

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.