Evidence map›Paper›PMID 33110951›Full record

ArticleDevelopment & reproduction2020

Altered Gene Expression Profiles in the Lungs of Streptozotocin-induced Diabetic Mice.

Jung-Hyun Kim, Roya Rasaei, Sujin Park, Ji-Young Kim, Sunghun Na, Seok-Ho Hong

Open access · diamondAbstract read
In one paragraph

Article in Development & reproduction, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jung-Hyun KimDept. of Internal Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.ORCID https://orcid.org/0000-0002-7901-4012
Roya RasaeiDept. of Internal Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.ORCID https://orcid.org/0000-0002-1880-095X
Sujin ParkDept. of Internal Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.ORCID https://orcid.org/0000-0002-4362-0846
Ji-Young KimDept. of Internal Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.ORCID https://orcid.org/0000-0002-0112-2603
Sunghun NaDept. of Obstetrics and Gynecology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.ORCID https://orcid.org/0000-0002-2803-8356
Seok-Ho HongDept. of Internal Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.ORCID https://orcid.org/0000-0003-3372-442X
Kangwon National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus is a common heterogeneous metabolic disorder, characterized by deposition of extracellular matrix, oxidative stress, and vascular dysfunction, thereby leading to gradual loss of function in multiple organs. However, little attention has been paid to gene expression changes in the lung under hyperglycemic conditions. In this study, we found that diabetes inuced histological changes in the lung of streptozotocin-induced diabetic mice. Global gene expression profiling revealed a set of genes that are up- and down-regulated in the lung of diabetic mice. Among these, expression of

Indexed as

DiabetesGene expression profileLungPerivascular cells

Identifiers

PMID33110951
PMCPMC7576965
OpenAlexW3094146005

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.