ArticleJournal of family medicine and primary care2020
A demographic prevalence of β Thalassemia carrier and other hemoglobinopathies in adolescent of Tharu population.
Article in Journal of family medicine and primary care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 19 citations in OpenAlex.
- Sickle Cell Disease in Eastern Uttar Pradesh, India: Sociodemographic and Clinical Profile from a Previously Undocumented Area.Journal of racial and ethnic health disparities · 2026Article
- Prevalence and Detection of Novel Thalassemia Variant hemoglobin J in Extensive Tharu Population.Annals of African medicine · 2025Article
- High-Resolution Genetic Profiling of Hb J-Meerut and Other Hemoglobin Variants in the Tharu Population via HPLC and DNA Sequencing.Diagnostics (Basel, Switzerland) · 2025Article
- Prevalence of beta thalassemia carriers in India: a systematic review and meta-analysis.Journal of community genetics · 2023Review
- Predicting Thalassemia Using Feature Selection Techniques: A Comparative Analysis.Diagnostics (Basel, Switzerland) · 2023Article
- Article
- Health status of tribes of Uttar Pradesh with special reference to health-seeking behaviour of unchartedThe Indian journal of medical research · 2022Review
- Prevalence of anemia among reproductive-age females in the Tharu tribe of the Indo-Nepal border region.Journal of family medicine and primary care · 2022Article
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10 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsHemoglobinopathies and thalassemias are the commonest single gene disorders in India. In Terai region of India, Hemoglobinopathies and thalassemias are the most common in the Tharu community. Therefore, in this study, we aim to evaluate the Hb variant analysis of hemoglobinopathies and thalassemias in a Tharu population in Lakhimpur Kheri Districts of Uttar Pradesh, India. MATERIALS AND
methodsTotal 493 individuals were recruited in this study. The demographic details and blood samples were collected from different location at Kheri district during mega health camp. Hb variant analysis was performed by high performance liquid chromatography (HPLC) system beta thalassemia short program in BIO-RAD VARIANT.
resultsOut of 493, 108 (21.9%) individual suffers with abnormal haemoglobinopathies. In which β-thalassemia trait is the commonest haemoglobinopathy (12.98%), followed by HbE trait (7.50%), and compound heterozygous HbS/β-Thalassemia trait (1.42%) in overall population. The HbF was significantly greater in HbS heterozygous (1.45 ± 1.41), whereas mean HbA2 was significantly greater in β-Thalassemia trait (5.17 ± 1.36).
conclusionThe high incidence of hemoglobinopathies and thalassemias were observed in Tharu community in Lakhimpur Kheri districts of Uttar Pradesh, Indian.
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