ArticleJournal of family medicine and primary care2020
Depression impedes neuroplasticity and quality of life after stroke.
Article in Journal of family medicine and primary care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
- A Systematic Scoping Review of Measures Used to Evaluate Treatment-Induced Changes in Depression, Anxiety, and Chronic Stress in People with Post-Stroke Aphasia.Aphasiology · 2025Article
- Prevalence and network structure of depression and its association with quality of life among older stroke survivors: findings from a national survey in China.General psychiatry · 2025Article
- Urdu translation and cross-cultural validation of neurological fatigue index on post stroke.BMC neurology · 2024Article
- Article
- Always Look on the Bright Side: Associations of Optimism With Functional Outcomes After Stroke.Journal of the American Heart Association · 2023Article
- Effects and central mechanism of electroacupuncture and MRI-navigated rTMS for PSD: study protocol for an fMRI-based single-center, randomized, controlled, open-label trial.Frontiers in psychiatry · 2023Article
- Emotional and qualitative outcomes among patients with left and right hemisphere stroke.Frontiers in neurology · 2022Article
- Reactive natural kinds and varieties of dependence.European journal for philosophy of science · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeDepression following a stroke/poststroke depression (PSD) has been newly recognized as one of the most common complications after stroke. PSD may affect neuroplasticity and quality of life. The purpose of present study was to find out effects of depression on functional recovery, quality of life and neuroplasticity in patients with acute stroke.
methodsA total of 76 cases were recruited for the study and out of which 44 were available for the analysis after six months. Patients were divided into three groups according to severity of depression: Group A (without depression), Group B (mild-to-moderate depression), and Group C (severe depression) on the basis of Patient Health Questionnaire-9 (PHQ-9) scale scores. All patients were assessed for depression by PHQ-9, and for quality of life by Stroke Specific Quality of Life (SSQOL) scale. Neuroplasticity was assessed by measuring levels of serum brain-derived neurotrophic factor.
resultsQuality of life was observed to be significantly affected by depression (
conclusionPSD is a serious complication, affecting quality of life and neuroplasticity (BDNF) in patients. Decreased neuroplasticity further may affect functional improvement.
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Registered trials
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