Evidence map›Paper›PMID 33110618›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

Enlarged perivascular spaces are not associated with vascular co-morbidities, clinical outcomes, and brain volumes in people with secondary progressive multiple sclerosis.

Lindsey Wooliscroft, Erin Boespflug, Andrea Hildebrand, Kathleen Shangraw, Elizabeth Silbermann, Dennis Bourdette, Rebecca Spain

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lindsey WooliscroftNeurology, Oregon Health & Science University, Portland, OR, USA.ORCID https://orcid.org/0000-0001-5377-6185
Erin BoespflugNeurology, Oregon Health & Science University, Portland, OR, USA.
Andrea HildebrandNeurology, Oregon Health & Science University, Portland, OR, USA.
Kathleen ShangrawNeurology, Oregon Health & Science University, Portland, OR, USA.
Elizabeth SilbermannNeurology, Oregon Health & Science University, Portland, OR, USA.
Dennis BourdetteNeurology, Oregon Health & Science University, Portland, OR, USA.
Rebecca SpainNeurology, Oregon Health & Science University, Portland, OR, USA.
Oregon Health & Science University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In secondary progressive multiple sclerosis (SPMS) significance of enlarged perivascular spaces (ePVS) is unknown.

Indexed as

atrophybiomarkersMRImultiple sclerosisoutcome measurementprogressive

Identifiers

PMID33110618
PMCPMC7557790
OpenAlexW3092861695

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.