Evidence map›Paper›PMID 33110595›Full record

ArticleJournal of global health2020

COVID-19 mortality among pregnant women in Mexico: A retrospective cohort study.

Mónica Ríos-Silva, Efrén Murillo-Zamora, Oliver Mendoza-Cano, Xóchitl Trujillo, Miguel Huerta

Open access · goldAbstract read
In one paragraph

Article in Journal of global health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Pooled it
  3. The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Pooled it
  4. Observational
  5. Article
  6. Review
  7. Are in-hospital COVID-19-related mortality and morbidity in pregnancy associated with gestational age?Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2022
    Article
  8. COVID-19 disease and vaccination in pregnant and lactating women.American journal of reproductive immunology (New York, N.Y. : 1989) · 2022
    Review
  9. Review
  10. COVID-19 and pregnancy: A comparison of case reports, case series and registry studies.European journal of obstetrics, gynecology, and reproductive biology · 2022
    Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Mónica Ríos-SilvaCentro Universitario de Investigaciones Biomédicas, Universidad de Colima, Colima, Mexico.
Efrén Murillo-ZamoraDepartamento de Epidemiología, Unidad de Medicina Familiar No. 19, Instituto Mexicano del Seguro Social, Colima, Colima, México.
Oliver Mendoza-CanoFacultad de Ingeniería Civil, Universidad de Colima, Coquimatlán, Colima, México.
Xóchitl TrujilloCentro Universitario de Investigaciones Biomédicas, Universidad de Colima, Colima, Mexico.
Miguel HuertaCentro Universitario de Investigaciones Biomédicas, Universidad de Colima, Colima, Mexico.
Universidad de Colima · MXMexican Social Security Institute · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPregnant women have been classified as at risk for COVID-19 due to previous experience with influenza and other coronaviruses. The objective of this study was to identify risk factors for the complications and death in women of childbearing age and pregnant women with suspected COVID-19.

methodsThis retrospective cohort study was conducted from the beginning of the epidemic in Mexico until May 25, 2020. All women of childbearing age (13-49 years) from the open national COVID-19 database from the Ministry of Health of Mexico were considered for eligibility. SARS-COV-2 infection was confirmed or ruled out by RT-qPCR. We performed a bivariate and multivariable analysis to estimate mortality risk.

resultsTen (2.2%) pregnant women with confirmed COVID-19 died. Positive pregnant patients did not have a higher risk of complications (admission to the ICU, pneumonia, or requirement for mechanical ventilation) or death than the controls. In the multivariate analysis, only history of diabetes and chronic kidney disease remained independently associated with death in the positive cohort. Seven (0.6%) pregnant women with a negative test died. In bivariate analysis, pregnant patients with a positive test had a higher risk of death than pregnant patients with a negative test (relative risk (RR) = 3.87, 95% confidence interval (CI) = 1.48-10.12), but no higher risk was found than in non-pregnant women with a positive test (RR = 0.82, 95% CI = 0.44-1.53), and 60-day mortality did not significantly differ among pregnant patients with or without a positive test (hazard ratio (HR) = 0.40, 95% CI = 0.12-1.30) or between COVID-19-positive patients who were pregnant or not pregnant (HR = 0.74, 95% CI = 0.35-1.56).

conclusionsPregnant patients do not have a greater risk of complications or death from COVID-19 than non-pregnant patients. The presence of diabetes mellitus and chronic disease increases the risk of death in women of childbearing age, but not specifically in pregnant patients.

Indexed as

BetacoronavirusAdultCoronavirus InfectionsCOVID-19FemaleHospitalizationHumansMexicoPandemicsPneumonia, ViralPregnancyPregnancy Complications, InfectiousRetrospective StudiesRisk FactorsSARS-CoV-2

Identifiers

PMID33110595
PMCPMC7567444
OpenAlexW3088294421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.