Evidence map›Paper›PMID 33110488›Full record

ArticleTherapeutic advances in endocrinology and metabolism2020

Prognostic significance of the sum of the diameters of single foci in multifocal papillary thyroid cancer: the concept of new-old tumor burden.

Jacopo Manso, Simona Censi, Amir Roberti, Maurizio Iacobone, Susi Barollo, Loris Bertazza, Francesca Galuppini, Federica Vianello, Nora Albinger, Carla Scaroni and 2 more

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in endocrinology and metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Jacopo MansoDepartment of Medicine (DIMED), Endocrine Unit, Università di Padova, Via Ospedale Civile 105, Padova, 35128, Italy.ORCID https://orcid.org/0000-0003-2403-4339
Simona CensiDepartment of Medicine (DIMED), Endocrinology Unit, Padua University, Padua, Italy.
Amir RobertiDepartment of Medicine (DIMED), Endocrinology Unit, Padua University, Padua, Italy.
Maurizio IacoboneDepartment of Surgical, Oncological and Gastroenterological Sciences (DiSCOG), Endocrine Surgery Unit, Padua University Hospital, Padua, Italy.
Susi BarolloDepartment of Medicine (DIMED), Endocrinology Unit, Padua University, Padua, Italy.
Loris BertazzaDepartment of Medicine (DIMED), Endocrinology Unit, Padua University, Padua, Italy.
Francesca GaluppiniDepartment of Medicine (DIMED), Surgical Pathology and Cytopathology Unit, Padua University, Padua, Italy.
Federica VianelloDepartment of Radiotherapy, Istituto Oncologico del Veneto, IOV-IRCCS, Padova, Italy.
Nora AlbingerDepartment of Radiotherapy, Istituto Oncologico del Veneto, IOV-IRCCS, Padova, Italy.
Carla ScaroniDepartment of Medicine (DIMED), Endocrinology Unit, Padua University, Padua, Italy.
Gianmaria PennelliDepartment of Medicine (DIMED), Surgical Pathology and Cytopathology Unit, Padua University, Padua, Italy.
Caterina MianDepartment of Medicine (DIMED), Endocrinology Unit, Padua University, Padua, Italy.
University of Padua · ITIstituto Oncologico Veneto · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe prognostic value of multifocality (Mu) in papillary thyroid cancer (PTC) remains controversial. The present study aimed to investigate this issue and test the possible prognostic significance of the sum of the diameters of single foci (SDSF), the total number of foci (TNF), and primary tumor size (PTS) in multifocal PTC.

methodsWe retrospectively analyzed a single-center consecutive series of 370 PTCs. For multifocal cases we analyzed bilaterality occurrence, SDSF, TNF, and PTS.

resultsMu was observed in 41.1% PTCs, and bilaterality in 30%. Mu was associated with an advanced T-category. In bilateral multifocal PTC, the PTS was larger, and microPTC was less frequent, while T-categories were higher. Mu and bilaterality

conclusionsMu and bilaterality

Indexed as

bilateralitymultifocalitypapillary thyroid cancersum of diameters of single focitumor burden

Identifiers

PMID33110488
PMCPMC7557686
OpenAlexW3092939985

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.