Evidence map›Paper›PMID 33110445›Full record

ArticleChild and adolescent psychiatry and mental health2020

"I feel good when I drink"-detecting childhood-onset alcohol abuse and dependence in a Ugandan community trial cohort.

Ingunn Marie Stadskleiv Engebretsen, Joyce S Nalugya, Vilde Skylstad, Grace Ndeezi, Angela Akol, Juliet N Babirye, Victoria Nankabirwa, James K Tumwine

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Child and adolescent psychiatry and mental health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04743024 (TREAT Child Alcohol Use Disorder), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04743024 unknown statusnot on this map

TREAT Child Alcohol Use Disorder (C-AUD) in Eastern Uganda: Screening, Diagnostics, Risk Factors and Handling of Children Drinking Alcohol

TypeobservationalSponsorUniversity of BergenRan2020 to 2025Enrolled7,188ConditionsAlcohol Abuse, Alcohol Drinking, Alcoholism, Alcohol Use Disorder
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Ingunn Marie Stadskleiv Engebretsen *Global Mental Health Research Group, Centre for International Health, Department of Global Public Health and Primary Health Care, Faculty of Medicine, University of Bergen, Bergen, Norway.ORCID 0000-0001-5852-3611
Joyce S Nalugya *Department of Psychiatry, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Vilde Skylstad *Global Mental Health Research Group, Centre for International Health, Department of Global Public Health and Primary Health Care, Faculty of Medicine, University of Bergen, Bergen, Norway.
Grace NdeeziDepartment of Paediatrics and Child Health, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Angela AkolGlobal Mental Health Research Group, Centre for International Health, Department of Global Public Health and Primary Health Care, Faculty of Medicine, University of Bergen, Bergen, Norway.
Juliet N BabiryeSchool of Public Health, College of Health Sciences, Makerere University, Kampala, Uganda.
Victoria NankabirwaSchool of Public Health, College of Health Sciences, Makerere University, Kampala, Uganda.
James K TumwineDepartment of Paediatrics and Child Health, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Makerere University · UGUniversity of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlcohol, substance use, and mental health disorders constitute major public health issues worldwide, including in low income and lower middle-income countries, and early initiation of use is an important predictor for developing substance use disorders in later life. This study reports on the existence of childhood alcohol abuse and dependence in a sub-study of a trial cohort in Eastern Uganda.

methodsThe project SeeTheChild-Mental Child Health in Uganda (STC) included a sub-study of the Ugandan site of the study PROMISE SB: Saving Brains in Uganda and Burkina Faso. PROMISE SB was a follow-up study of a trial birth cohort (PROMISE EBF) that estimated the effect that peer counselling for exclusive breast-feeding had on the children's cognitive functioning and mental health once they reached 5-8 years of age. The STC sub-study (N = 148) used the diagnostic tool MINI-KID to assess mental health conditions in children who scored medium and high (≥ 14) on the Strengths and Difficulties Questionnaire (SDQ) in the PROMISE SB cohort N = (119/148; 80.4%). Another 29/148 (19.6%) were recruited from the PROMISE SB cohort as a comparator with low SDQ scores (< 14). Additionally, the open-ended questions in the diagnostic history were analysed. The MINI-KID comprised diagnostic questions on alcohol abuse and dependence, and descriptive data from the sub-study are presented in this paper.

resultsA total of 11/148 (7.4%) children scored positive for alcohol abuse and dependence in this study, 10 of whom had high SDQ scores (≥ 14). The 10 children with SDQ-scores ≥ 14 had a variety of mental health comorbidities of which suicidality 3/10 (30.0%) and separation anxiety disorder 5/10 (50.0%) were the most common. The one child with an SDQ score below 14 did not have any comorbidities. Access to homemade brew, carer's knowledge of the drinking, and difficult household circumstances were issues expressed in the children's diagnostic histories.

conclusionsThe discovery of alcohol abuse and dependence among 5-8 year olds in clinical interviews from a community based trial cohort was unexpected, and we recommend continued research and increased awareness of these conditions in this age group.

Indexed as

Alcohol abuseAlcohol dependenceAlcoholismAlcohol use disorderChild developmentChildhoodCommunity cohortDSM-IVEarly onsetMental healthMINI-KIDUganda

Identifiers

PMID33110445
PMCPMC7585688
OpenAlexW3094136577

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.