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ArticleFrontiers in psychiatry2020

Club Drugs: Psychotropic Effects and Psychopathological Characteristics of a Sample of Inpatients.

Giovanni Martinotti, Attilio Negri, Stefania Schiavone, Chiara Montemitro, Chiara Vannini, Gaia Baroni, Mauro Pettorruso, Fabio De Giorgio, Raffaele Giorgetti, Valeria Verrastro and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Knowledge and Use of Novel Psychoactive Substances in an Italian Sample with Substance Use Disorders.International journal of environmental research and public health · 2022
    Article
  6. Article
  7. Prevalence of and Factors Associated with Club Drug Use among Secondary Vocational Students in China.International journal of environmental research and public health · 2021
    Article
  8. Club Drugs and Psychiatric Sequelae: An Issue of Vulnerability and Previous Psychiatric History.International journal of environmental research and public health · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 3 countries.

Giovanni MartinottiDepartment of Neuroscience, Imaging, Clinical Sciences, University G.d'Annunzio Chieti-Pescara, Chieti, Italy.
Attilio NegriDepartment of Pharmacy, Pharmacology and Clinical Science, University of Hertfordshire, Hatfield, United Kingdom.
Stefania SchiavoneDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Chiara MontemitroDepartment of Neuroscience, Imaging, Clinical Sciences, University G.d'Annunzio Chieti-Pescara, Chieti, Italy.
Chiara VanniniDepartment of Neuroscience, Imaging, Clinical Sciences, University G.d'Annunzio Chieti-Pescara, Chieti, Italy.
Gaia BaroniDepartment of Neuroscience, Imaging, Clinical Sciences, University G.d'Annunzio Chieti-Pescara, Chieti, Italy.
Mauro PettorrusoDepartment of Neuroscience, Imaging, Clinical Sciences, University G.d'Annunzio Chieti-Pescara, Chieti, Italy.
Fabio De GiorgioSection of Legal Medicine, Department of Health Care Surveillance and Bioethics, Università Cattolica del Sacro Cuore, Rome, Italy.
Raffaele GiorgettiSection of Legal Medicine, Department of Excellence SBSP, University "Politecnica delle Marche" of Ancona, Ancona, Italy.
Valeria VerrastroDepartment of Medical and Surgical Sciences, Magna Graecia University of Catanzaro, Catanzaro, Italy.
Luigia TrabaceDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Andres GarciaEmergency Staff Group, Ibiza, Spain.
Ivan CastroEmergency Staff Group, Ibiza, Spain.
Juan Iglesias LopezCan Misses Hospital, Ibiza, Spain.
Cristina Merino Del VillarCan Misses Hospital, Ibiza, Spain.
Fabrizio SchifanoDepartment of Pharmacy, Pharmacology and Clinical Science, University of Hertfordshire, Hatfield, United Kingdom.
Massimo di GiannantonioDepartment of Neuroscience, Imaging, Clinical Sciences, University G.d'Annunzio Chieti-Pescara, Chieti, Italy.
University of Chieti-Pescara · ITHospital Can Misses · ESUniversity of Foggia · ITUniversity of Hertfordshire · GBAgostino Gemelli University Polyclinic · ITMagna Graecia University · ITMarche Polytechnic University · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGrowing evidence supports the possibility of significant psychiatric consequences related to novel and traditional psychoactive substance consumption. The problem of differential diagnosis has hampered research on specific psychopathologies with unclear outcomes. The aim of our study was to report psychiatric and clinical features of subjects admitted to a psychiatric ward in Ibiza, Spain, with a clinical diagnosis of substance abuse or intoxication.

methodsA survey was administered to a sample of inpatients hospitalized due to psychiatric symptoms related to recent use of psychoactive substances. The questionnaire investigated sociodemographic factors, familiar and personal anamnesis, substance use habits, general and psychopathological features. Urine samples were collected and analyzed in a toxicology laboratory using gas chromatography and mass spectrometry.

resultsA total of 110 patients were included in the study. Most patients (70%) declared multiple substance use, and 33% of patients reported more than two substances; nevertheless, it was possible to identify 17 (15%) depressor users, 44 (40%) stimulant users and 49 (45%) psychodysleptics users. A positive association with a lifetime diagnosis of bipolar disorder was found (two-tailed Fisher's exact test: p = 0.013). Psychomotor agitation, reference, and paranoid delusions, affective symptoms, consciousness disorders, and aggressiveness represented some of the most frequent symptoms at entry evaluation.

conclusionsIn this study, we described the acute psychiatric presentations related to recreational drug use in subjects on holiday in Ibiza. The use of psychoactive substances was characterized by poly-use of both traditional and novel substances, with several psychopathological consequences. Future research should focus on a better understanding of the psychopathological effects of specific substances, defining signs and symptoms to help make a differential diagnosis and prospectively examine long-term effects.

Indexed as

club drugsnovel psychoactive substancespsychopathologypsychosissubstance use disorder

Identifiers

PMID33110412
PMCPMC7488956
OpenAlexW3082271913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.