Evidence map›Paper›PMID 33110301›Full record

ReviewContemporary clinical dentistry

Meta-Analysis of Risk Association between Interleukin-17A Gene Polymorphism and Chronic Periodontitis.

P K Sasikumar, Sheeja S Varghese, Thanga Kumaran, Sakthi Saranya Devi

Open access · goldAbstract readReview
In one paragraph

Review in Contemporary clinical dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. The Role of IL-17 in Periodontitis and Its Systemic Connections.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

P K SasikumarDepartment of Periodontics, JKKN Dental College, Namakkal, Tamil Nadu, India.
Sheeja S VargheseDepartment of Periodontics, Saveetha Dental College, Chennai, Tamil Nadu, India.
Thanga KumaranDepartment of Periodontics, JKKNDCH, Thiruchengodu, Tamil Nadu, India.
Sakthi Saranya DeviDepartment of Oral Medicine Andradiology, KSR Institute of Dental Science and Research, Thiruchengodu, Tamil Nadu, India.
Saveetha University · INChristie's · GBKamineni Institute of Dental Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a critical role in inflammatory diseases and periodontal inflammation. The present study was aimed at pooling the data available for meta-analysis and to evaluate whether IL-17A (rs2275913) polymorphism is associated with the susceptibility of chronic periodontitis.

Indexed as

Chronic periodontitisethnicityinterleukin-17A geneinterleukin-17A polymorphism

Identifiers

PMID33110301
PMCPMC7580746
OpenAlexW3041392047

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.