Evidence map›Paper›PMID 33110193›Full record

ArticleScientific reports2020

Atherosclerotic plaque vulnerability is increased in mouse model of lupus.

Marie-Laure Santiago-Raber, Fabrizio Montecucco, Nicolas Vuilleumier, Kapka Miteva, Daniela Baptista, Federico Carbone, Sabrina Pagano, Aline Roth, Fabienne Burger, Francois Mach and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
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  5. Review
  6. Accelerated atherosclerosis in beta-thalassemia.American journal of physiology. Heart and circulatory physiology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Effects of swimming on the development of atherosclerosis in mice.American journal of translational research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 3 countries.

Marie-Laure Santiago-RaberDepartment of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Fabrizio MontecuccoOspedale Policlinico San Martino Genoa-Italian Cardiovascular Network, 10 Largo Benzi, 16132, Genoa, Italy.ORCID 0000-0003-0823-8729
Nicolas VuilleumierDepartment of Genetic Medicine, Laboratory and Pathology, Geneva University Hospitals, Geneva, Switzerland.
Kapka MitevaDivision of Cardiology, Foundation for Medical Researches, Department of Medicine Specialties, Faculty of Medicine, University of Geneva, Av. de la Roseraie 64, 1211, Geneva 4, Switzerland.
Daniela BaptistaDivision of Cardiology, Foundation for Medical Researches, Department of Medicine Specialties, Faculty of Medicine, University of Geneva, Av. de la Roseraie 64, 1211, Geneva 4, Switzerland.
Federico CarboneOspedale Policlinico San Martino Genoa-Italian Cardiovascular Network, 10 Largo Benzi, 16132, Genoa, Italy.ORCID 0000-0003-2957-4078
Sabrina PaganoDepartment of Genetic Medicine, Laboratory and Pathology, Geneva University Hospitals, Geneva, Switzerland.
Aline RothDivision of Cardiology, Foundation for Medical Researches, Department of Medicine Specialties, Faculty of Medicine, University of Geneva, Av. de la Roseraie 64, 1211, Geneva 4, Switzerland.
Fabienne BurgerDivision of Cardiology, Foundation for Medical Researches, Department of Medicine Specialties, Faculty of Medicine, University of Geneva, Av. de la Roseraie 64, 1211, Geneva 4, Switzerland.
Francois MachDivision of Cardiology, Foundation for Medical Researches, Department of Medicine Specialties, Faculty of Medicine, University of Geneva, Av. de la Roseraie 64, 1211, Geneva 4, Switzerland.
Karim J BrandtDivision of Cardiology, Foundation for Medical Researches, Department of Medicine Specialties, Faculty of Medicine, University of Geneva, Av. de la Roseraie 64, 1211, Geneva 4, Switzerland. karim.brandt@hcuge.ch.ORCID 0000-0003-1042-5283
University of Geneva · CHOspedale Policlinico San Martino · IT

Funding

Swiss National Science Foundation 310030_152912/1
6 · The paper itself

Abstract

Anti-apolipoprotein A-1 (anti-apoA-1 IgG) and anti-double stranded DNA (anti-dsDNA IgG) autoantibodies have been described as mediators of atherogenesis in mice and humans. In the present study, we aim to investigate the association between atherosclerotic parameters, autoantibodies and plaque vulnerability in the context of systemic lupus erythematosus (SLE). We therefore bred a lupus prone-mouse model (Nba2.Yaa mice) with Apoe

Indexed as

AnimalsAutoantibodiesDisease Models, AnimalDisease SusceptibilityEnzyme-Linked Immunosorbent AssayLupus Erythematosus, SystemicMiceMice, Inbred C57BLMice, KnockoutPlaque, AtheroscleroticReal-Time Polymerase Chain ReactionSinus of ValsalvaAutoantibodies

Identifiers

PMID33110193
PMCPMC7591560
OpenAlexW3096596000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.