Evidence map›Paper›PMID 33110127›Full record

ArticleScientific reports2020

Prediction and detection of human epileptic seizures based on SIFT-MS chemometric data.

Amélie Catala, Cecile Levasseur-Garcia, Marielle Pagès, Jean-Luc Schaff, Ugo Till, Leticia Vitola Pasetto, Martine Hausberger, Hugo Cousillas, Frederic Violleau, Marine Grandgeorge

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amélie CatalaAssociation Handi'Chiens, 13 Rue de l'Abbé Groult, Paris, France. amelie.catala@gmail.com.
Cecile Levasseur-GarciaLaboratoire de Chimie Agro-industrielle (LCA), Université de Toulouse, INRA, University of Toulouse, National Polytechnic Institute of Toulouse, Ecole d'ingénieurs de Purpan, Toulouse, France.
Marielle PagèsEquipe Physiologie, Pathologie et Génétique Végétales (PPGV), University of Toulouse, National Polytechnic Institute of Toulouse, Ecole d'ingénieurs de Purpan, 75 voie du TOEC, BP 57611, 31076, Toulouse Cedex 03, France.
Jean-Luc SchaffService de Neurologie du CHRU de Nancy, 29, avenue du Maréchal de Lattre de Tassigny, Nancy, France.
Ugo Till, Laval, France.
Leticia Vitola PasettoLaboratoire de Chimie Agro-industrielle (LCA), Université de Toulouse, INRA, University of Toulouse, National Polytechnic Institute of Toulouse, Ecole d'ingénieurs de Purpan, Toulouse, France.
Martine HausbergerUniv Rennes, Normandie Univ, CNRS, EthoS (Éthologie animale et humaine), UMR 6552, 35000, Rennes, France.
Hugo CousillasUniv Rennes, Normandie Univ, CNRS, EthoS (Éthologie animale et humaine), UMR 6552, 35000, Rennes, France.
Frederic ViolleauLaboratoire de Chimie Agro-industrielle (LCA), Université de Toulouse, INRA, University of Toulouse, National Polytechnic Institute of Toulouse, Ecole d'ingénieurs de Purpan, Toulouse, France.
Marine GrandgeorgeUniv Rennes, Normandie Univ, CNRS, EthoS (Éthologie animale et humaine), UMR 6552, 35000, Rennes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although epilepsy is considered a public health issue, the burden imposed by the unpredictability of seizures is mainly borne by the patients. Predicting seizures based on electroencephalography has had mixed success, and the idiosyncratic character of epilepsy makes a single method of detection or prediction for all patients almost impossible. To address this problem, we demonstrate herein that epileptic seizures can not only be detected by global chemometric analysis of data from selected ion flow tube mass spectrometry but also that a simple mathematical model makes it possible to predict these seizures (by up to 4 h 37 min in advance with 92% and 75% of samples correctly classified in training and leave-one-out-cross-validation, respectively). These findings should stimulate the development of non-invasive applications (e.g., electronic nose) for different types of epilepsy and thereby decrease of the unpredictability of epileptic seizures.

Indexed as

Breath TestsHumansMass SpectrometryOdorantsReproducibility of ResultsSeizuresSensitivity and SpecificityVolatile Organic CompoundsVolatile Organic Compounds

Identifiers

PMID33110127
PMCPMC7591930

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.