ArticleNature communications2020
Disease burden and clinical severity of the first pandemic wave of COVID-19 in Wuhan, China.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Psychological distress among nursing students during the COVID-19 pandemic: a hybrid concept analysis.BMC psychology · 2025Pooled it
- The role of respiratory co-infection with influenza or respiratory syncytial virus in the clinical severity of COVID-19 patients: A systematic review and meta-analysis.Journal of global health · 2022Pooled it
- Epidemiology of SARS-CoV-2 Infection in Italy Using Real-World Data: Methodology and Cohort Description of the Second Phase of Web-Based EPICOVID19 Study.International journal of environmental research and public health · 2022Trial
- Multidimensional drivers of diabetes prevalence among middle-aged and elderly in China: from a geographical perspective.Diabetology & metabolic syndrome · 2026Article
- COVID-19 vaccine compliance among pregnant women in Poland during the pandemic.Frontiers in public health · 2026Article
- COVID-19 symptomatic community illness, hospitalization, and death burden across all ages - New South Wales, Australia, May 2021-July 2022.BMC public health · 2025Article
- Association of Haptoglobin Heterozygosity (HP1-2) with the Risk of COVID-19 Infection in a Sample of the Iranian Population.Reports of biochemistry & molecular biology · 2025Article
- Exposure to Concurrent Heatwaves and Ozone Pollution and Associations with Mortality Risk: A Nationwide Study in China.Environmental health perspectives · 2024Article
- Article
- Effectiveness of a scenario-based, community-based intervention in containing COVID-19 in China.Frontiers in public health · 2024Article
- Reversible rearrangement of the cellular cytoskeleton: A key to the broad-spectrum antiviral activity of novel amphiphilic polymers.Materials today. Bio · 2023Article
- Bayesian sequential approach to monitor COVID-19 variants through test positivity rate from wastewater.mSystems · 2023Article
- Bayesian sequential approach to monitor COVID-19 variants through positivity rate from wastewater.medRxiv : the preprint server for health sciences · 2023Article
- Development and Validation of a Prediction Model of the Risk of Pneumonia in Patients with SARS-CoV-2 Infection.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023Article
- Assessing the transition of COVID-19 burden towards the young population while vaccines are rolled out in China.Emerging microbes & infections · 2022Article
- Clinical features and viral etiology of acute respiratory infection in an outpatient fever clinic during COVID-19 pandemic in a tertiary hospital in Nanjing, China.Journal of clinical laboratory analysis · 2022Article
- Confronting SARS-CoV-2 Infection: Patients' Experience in the First Pandemic Wave-Cross-Sectional Study.International journal of environmental research and public health · 2022Article
- The molecular epidemiology of multiple zoonotic origins of SARS-CoV-2.Science (New York, N.Y.) · 2022Article
- Analysis of influenza trend and impact of COVID-19 in Kezhou, Xinjiang for 8 consecutive years.Journal of medical virology · 2022Article
- Quantifying human mixing patterns in Chinese provinces outside Hubei after the 2020 lockdown was lifted.BMC infectious diseases · 2022Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
- Update of
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The novel coronavirus disease 2019 (COVID-19) was first reported in Wuhan, China, where the initial wave of intense community transmissions was cut short by interventions. Using multiple data sources, here we estimate the disease burden and clinical severity by age of COVID-19 in Wuhan from December 1, 2019 to March 31, 2020. Our estimates account for the sensitivity of the laboratory assays, prospective community screenings, and healthcare seeking behaviors. Rates of symptomatic cases, medical consultations, hospitalizations and deaths were estimated at 796 (95% CI: 703-977), 489 (472-509), 370 (358-384), and 36.2 (35.0-37.3) per 100,000 persons, respectively. The COVID-19 outbreak in Wuhan had a higher burden than the 2009 influenza pandemic or seasonal influenza in terms of hospitalization and mortality rates, and clinical severity was similar to that of the 1918 influenza pandemic. Our comparison puts the COVID-19 pandemic into context and could be helpful to guide intervention strategies and preparedness for the potential resurgence of COVID-19.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.