Evidence map›Paper›PMID 33109767›Full record

ArticlemBio2020

Estimation of Full-Length TprK Diversity in Treponema pallidum subsp.

Amin Addetia, Michelle J Lin, Quynh Phung, Hong Xie, Meei-Li Huang, Giulia Ciccarese, Ivano Dal Conte, Marco Cusini, Francesco Drago, Lorenzo Giacani and 1 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. The Global Syphilis Epidemic: Turning the Tide.Sexually transmitted diseases · 2026
    Article
  2. Article
  3. Lineage-specificbioRxiv : the preprint server for biology · 2026
    Article
  4. Frontiers in immunology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Longitudinal Variations in theMicrobiology spectrum · 2023
    Article
  11. Genetic Profiling of the Full-LengthMicrobiology spectrum · 2023
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Notes on syphilis vaccine development.Frontiers in immunology · 2022
    Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Amin AddetiaDepartment of Laboratory Medicine, University of Washington, Seattle, Washington, USA.
Michelle J LinDepartment of Laboratory Medicine, University of Washington, Seattle, Washington, USA.
Quynh PhungDepartment of Laboratory Medicine, University of Washington, Seattle, Washington, USA.
Hong XieDepartment of Laboratory Medicine, University of Washington, Seattle, Washington, USA.
Meei-Li HuangDepartment of Laboratory Medicine, University of Washington, Seattle, Washington, USA.
Giulia CiccareseHealth Sciences Department, Section of Dermatology, San Martino University Hospital, Genoa, Italy.
Ivano Dal ConteSTI Clinic, Amedeo di Savoia Hospital, University of Turin, Turin, Italy.
Marco CusiniFondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Francesco DragoHealth Sciences Department, Section of Dermatology, San Martino University Hospital, Genoa, Italy.
Lorenzo GiacaniDepartment of Medicine, University of Washington, Seattle, Washington, USA.
Alexander L GreningerDepartment of Laboratory Medicine, University of Washington, Seattle, Washington, USA agrening@uw.edu.ORCID 0000-0002-7443-0527
University of Washington · USFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITOspedale Amedeo di Savoia · IT

Funding

Urethral microbiome and non-gonococcal urethritis in men who have sex with men (MU19AI113173 · NIAID · UNIVERSITY OF WASHINGTON · PI MARRAZZO, JEANNE M · 2014 to 2018
$14.3M
University of Washington (UW) Sexually Transmitted Infections (STI) Cooperative Research Center (CRC) - Syphilis Vaccine to Protect against Local and Disseminated T. pallidum InfectionU19AI144133 · NIAID · UNIVERSITY OF WASHINGTON · PI WALD, ANNA · 2019 to 2023
$10.6M
NIAID NIH HHS U19 AI113173NIAID NIH HHS U19 AI144133
6 · The paper itself

Abstract

Immune evasion and disease progression of

Indexed as

Antigenic VariationSequence Analysis, DNAAdultAnimalsBacterial Outer Membrane ProteinsBacterial ProteinsGenomicsHigh-Throughput Nucleotide SequencingHumansImmune EvasionItalyMaleMiddle AgedPorinsRabbitsSyphilisBacterial Outer Membrane ProteinsBacterial Proteinsmajor outer sheath protein, TreponemaPorinsgene conversionimmune evasionPacBiosyphilisT. pallidumtprKtreponema

Identifiers

PMID33109767
PMCPMC7593977
OpenAlexW3096293062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.