Evidence map›Paper›PMID 33109762›Full record

ArticlemBio2020

A CozE Homolog Contributes to Cell Size Homeostasis of Streptococcus pneumoniae.

Gro Anita Stamsås, Marine Restelli, Adrien Ducret, Céline Freton, Pierre Simon Garcia, Leiv Sigve Håvarstein, Daniel Straume, Christophe Grangeasse, Morten Kjos

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Penicillin-Binding Proteins inAntibiotics (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Characterization of MreCD inJournal of oral microbiology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Gro Anita Stamsås *Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Marine Restelli *Molecular Microbiology and Structural Biochemistry, CNRS, Université de Lyon, Lyon, France.
Adrien DucretMolecular Microbiology and Structural Biochemistry, CNRS, Université de Lyon, Lyon, France.
Céline FretonMolecular Microbiology and Structural Biochemistry, CNRS, Université de Lyon, Lyon, France.
Pierre Simon GarciaMolecular Microbiology and Structural Biochemistry, CNRS, Université de Lyon, Lyon, France.
Leiv Sigve HåvarsteinFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Daniel StraumeFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Christophe GrangeasseMolecular Microbiology and Structural Biochemistry, CNRS, Université de Lyon, Lyon, France christophe.grangeasse@ibcp.fr morten.kjos@nmbu.no.ORCID 0000-0002-5484-4589
Morten KjosFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway christophe.grangeasse@ibcp.fr morten.kjos@nmbu.no.ORCID 0000-0003-4448-9082
Université Claude Bernard Lyon 1 · FRNorwegian University of Life Sciences · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Control of peptidoglycan assembly is critical to maintain bacterial cell size and morphology. Penicillin-binding proteins (PBPs) are crucial enzymes for the polymerization of the glycan strand and/or their cross-linking via peptide branches. Over the last few years, it has become clear that PBP activity and localization can be regulated by specific cognate regulators. The first regulator of PBP activity in Gram-positive bacteria was discovered in the human pathogen

Indexed as

HomeostasisAnti-Bacterial AgentsBacterial ProteinsComputational BiologyMembrane ProteinsMicrobial Sensitivity TestsMutationPenicillin-Binding ProteinsPeptidoglycanPhenotypeStreptococcus pneumoniaeAnti-Bacterial AgentsBacterial ProteinsMembrane ProteinsPenicillin-Binding ProteinsPeptidoglycancell divisionmorphogenesispenicillin-binding proteinspeptidoglycan

Identifiers

PMID33109762
PMCPMC7593971
OpenAlexW3094758215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.